Results 31 to 40 of about 6,611,862 (305)

Benefattori dall’aldilà: i lasciti per i lavori edilizi di pubblica utilità a Bologna (secoli XIII e XIV)

, 2021
La trattazione riguarda i benefattori, i donatori che hanno deciso a Bologna di contribuire al bene comune non tramite le tradizionali istituzioni caritatevoli, quali ospedali, conventi e monasteri, ma anche attraverso l’investimento dei loro beni nel ...
Edward Loss
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The shape of human gene family phylogenies [PDF]

, 2006
Background: The shape of phylogenetic trees has been used to make inferences about the evolutionary process by comparing the shapes of actual phylogenies with those expected under simple models of the speciation process. Previous studies have focused
James A Cotton, Page, R.D.M., Cotton James A, Roderic DM Page, Page Roderic DM, Cotton, J.A.   +5 more
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The economics of organellar gene loss and endosymbiotic gene transfer [PDF]

Genome Biology, 2020
Abstract The endosymbiosis of the bacterial progenitors of mitochondrion and the chloroplast are landmark events in the evolution of life on earth. While both organelles have retained substantial proteomic and biochemical complexity, this complexity is not reflected in the content of their genomes. Instead, the organellar genomes encode
openaire   +4 more sources

Evolutionary Histories of Type III Polyketide Synthases in Fungi

Frontiers in Microbiology, 2020
Type III polyketide synthases (PKSs) produce secondary metabolites with diverse biological activities, including antimicrobials. While they have been extensively studied in plants and bacteria, only a handful of type III PKSs from fungi has been ...
Jorge Carlos Navarro-Muñoz, Jérôme Collemare   +1 more
doaj   +1 more source

Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer. [PDF]

, 2010
BACKGROUND: The discovery of ERG/ETV1 gene rearrangements and PTEN gene loss warrants investigation in a mechanism-based prognostic classification of prostate cancer (PCa).
P T Scardino, Reid, A. H. M., D Brewer, Clark, J, S Edwards, H Møller, Kovacs, G., Gerald, W. L., Cuzick, J, Ambroisine, L., Cooper, C S, D M Berney, G Attard, de Bono, J S, J Cuzick, Cuzick, J., Reid, A H M, C S Cooper, Foster, C. S., Fletcher, A., Scardino, P. T., Fisher, G, Møller, H, Brewer, D, G Fisher, C S Foster, A Fletcher, Scardino, P T, Flohr, P., Scardino, PT, J S de Bono, de Bono, J. S., V E Reuter, Reuter, V. E., Cooper, CS, Edwards, S., de Bono, JS, G Kovacs, J Clark, Brewer, D., Attard, G, Fletcher, A, P Flohr, Flohr, P, Berney, D. M., Moller, H.; id_orcid, A H M Reid, Attard, G., Kovacs, G, Berney, DM, Edwards, S, L Ambroisine, Fisher, G., Foster, C S, Reuter, V E, Clark, J., Gerald, WL, Transatlantic Prostate Group, W L Gerald, Ambroisine, L, Reid, AHM, Foster, CS, Reuter, VE, Cooper, C. S., Gerald, W L, Berney, D M   +65 more
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Genetic Hearing Loss and Gene Therapy [PDF]

Genomics & Informatics, 2018
Genetic hearing loss crosses almost all the categories of hearing loss which includes the following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital, progressive, and adult onset; high-frequency, low-frequency, or mixed frequency; mild or profound; and recessive, dominant, or sex-linked.
Nathanial T Carpena, Min Young Lee
openaire   +3 more sources

Dynamic Evolution of Avian RNA Virus Sensors: Repeated Loss of RIG-I and RIPLET

Viruses, 2022
Retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5) are key RNA virus sensors belonging to the RIG-I-like receptor (RLR) family.
Veronika Krchlíková, Tomáš Hron, Martin Těšický, Tao Li, Lenka Ungrová, Jiří Hejnar, Michal Vinkler, Daniel Elleder   +7 more
doaj   +1 more source

Loss of dispensable genes is not adaptive in yeast [PDF]

Proceedings of the National Academy of Sciences, 2005
A substantial share of genes identified in yeast can be deleted without visible phenotypic effects. Current debate concentrates on the possible roles of seemingly dispensable genes. The costs of maintaining unnecessary functions has attracted little attention. The hypothesis of antagonistic pleiotropy postulates that adaptations to
Sliwa, Piotr, Korona, Ryszard
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The Vertebrate TLR Supergene Family Evolved Dynamically by Gene Gain/Loss and Positive Selection Revealing a Host–Pathogen Arms Race in Birds

Diversity, 2019
The vertebrate toll-like receptor (TLRs) supergene family is a first-line immune defense against viral and non-viral pathogens. Here, comparative evolutionary-genomics of 79 vertebrate species (8 mammals, 48 birds, 11 reptiles, 1 amphibian, and 11 fishes)
Imran Khan, Emanuel Maldonado, Liliana Silva, Daniela Almeida, Warren E. Johnson, Stephen J. O’Brien, Guojie Zhang, Erich D. Jarvis, M. Thomas P. Gilbert, Agostinho Antunes   +9 more
doaj   +1 more source

Association of the CCR5 gene with juvenile idiopathic arthritis [PDF]

, 2010
The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction.
Martin, P., BSPAR Study Group, Barton, A., UKRAG Consortium, Worthington, J., Gardner-Medwin, J. [CAPS and BSPAR Study Groups], Thomson, W., W Thomson, Flynn, E., A Hinks, E Flynn, J Packham, Packham, J., Hinks, A., S Eyre, J Worthington, Eyre, S.; id_orcid, Eyre, S., Barton, A.; id_orcid, P Martin, Childhood Arthritis Prospective Study (CAPS), Martin, P.; id_orcid, A Barton   +22 more
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