Results 51 to 60 of about 1,645,919 (262)

Plant protein-coding gene families: Their origin and evolution

open access: yesFrontiers in Plant Science, 2022
Steady advances in genome sequencing methods have provided valuable insights into the evolutionary processes of several gene families in plants. At the core of plant biodiversity is an extensive genetic diversity with functional divergence and expansion ...
Yuanpeng Fang   +8 more
doaj   +1 more source

Selection-Driven Gene Loss in Bacteria

open access: yesPLoS Genetics, 2012
Gene loss by deletion is a common evolutionary process in bacteria, as exemplified by bacteria with small genomes that have evolved from bacteria with larger genomes by reductive processes. The driving force(s) for genome reduction remains unclear, and here we examined the hypothesis that gene loss is selected because carriage of superfluous genes ...
Koskiniemi S   +3 more
openaire   +5 more sources

Duplication and Losses of Opsin Genes in Lophotrochozoan Evolution

open access: yesMolecular Biology and Evolution, 2022
Abstract Opsins are G-coupled receptors playing a key role in metazoan visual processes. While many studies enriched our understanding of opsin diversity in several animal clades, the opsin evolution in Lophotrochozoa, one of the major metazoan groups, remains poorly understood.
Giacinto De Vivo   +4 more
openaire   +3 more sources

Chloroplast Genome Evolution in Four Montane Zingiberaceae Taxa in China

open access: yesFrontiers in Plant Science, 2022
Chloroplasts are critical to plant survival and adaptive evolution. The comparison of chloroplast genomes could provide insight into the adaptive evolution of closely related species. To identify potential adaptive evolution in the chloroplast genomes of
Qian Yang   +9 more
doaj   +1 more source

Defining pathogenic bacterial species in the genomic era

open access: yesFrontiers in Microbiology, 2011
Actual definitions of bacterial species are limited due to the current criteria of definition and the use of restrictive genetic tools. The 16S rRNA sequence, for example, has been widely used as a marker for phylogenetic analyses; however, its use often
Kalliopi eGeorgiades, Didier eRaoult
doaj   +1 more source

Horizontal Transfer and Gene Loss Shaped the Evolution of Alpha-Amylases in Bilaterians

open access: yesG3: Genes, Genomes, Genetics, 2020
The subfamily GH13_1 of alpha-amylases is typical of Fungi, but it is also found in some unicellular eukaryotes (e.g., Amoebozoa, choanoflagellates) and non-bilaterian Metazoa.
Andrea Desiderato   +3 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Loss of heterozygosity and loss of expression of the DCC gene in gastric cancer. [PDF]

open access: yesJournal of Clinical Pathology, 1998
AIM: To investigate the role of DCC gene inactivation in the development and progression of gastric cancer. METHODS: Loss of heterozygosity and loss of expression of the DCC gene was studied in 51 surgical specimens of gastric cancer using detection based on polymerase chain reaction.
Fang, Dian-Chun   +2 more
openaire   +4 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Loss of Wood Formation Genes in Monocot Genomes [PDF]

open access: yesGenome Biology and Evolution, 2019
AbstractWoodiness (secondary xylem derived from vascular cambium) has been gained and lost multiple times in the angiosperms, but has been lost ancestrally in all monocots. Here, we investigate the conservation of genes involved in xylogenesis in fully sequenced angiosperm genomes, hypothesizing that monocots have lost some essential orthologs involved
Danielle Roodt   +3 more
openaire   +4 more sources

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