Results 21 to 30 of about 6,611,862 (305)
Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families [PDF]
, 2008 Recent studies have identified 2 loss-of-function variants, R501X and 2282del4, in the filaggrin gene as predisposing factors in the development of eczema.
Link, Jenny +15 more
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Update on Viral Gene Therapy Clinical Trials for Retinal Diseases [PDF]
, 2022 In 2001, the first large animal was successfully treated with a gene therapy that restored its vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness called Leber's congenital amaurosis type 2.
Cheng, Shun-Yun, Punzo, Claudio
core +1 more source
Gene Gain and Gene Loss in Streptococcus: Is It Driven by Habitat? [PDF]
Molecular Biology and Evolution, 2006 Bacterial genomes can evolve either by gene gain, gene loss, mutating existing genes, and/or by duplication of existing genes. Recent studies have clearly demonstrated that the acquisition of new genes by lateral gene transfer (LGT) is a predominant force in bacterial evolution.
Pradeep Reddy, Marri +2 more
openaire +2 more sources
Frontiers in Microbiology, 2012 Mercuric mercury (Hg[II]) is a highly toxic and mobile element that is likely to have had a pronounced and adverse effect on biology since Earth’s oxygenation ~2.4 Gy ago due to its high affinity for protein sulfhydryl groups, which upon binding ...
Eric eBoyd, Tamar eBarkay
doaj +1 more source
Frontiers in Genetics, 2020 The family Orobanchaceae including autotrophic, hemiparasitic, and holoparasitic species, is becoming a key taxa to study the evolution of chloroplast genomes in different lifestyles. But the early evolutionary trajectory in the transit from autotrophism
Ruiting Zhang +8 more
doaj +1 more source
GENE LOSS IN HUMAN TERATOMAS [PDF]
Proceedings of the National Academy of Sciences, 1969 If benign cystic teratomas (dermoid cysts) of the ovary arise from a germ cell that has undergone meiosis, they should be missing genes which are present in the person. Three independently segregating allelic isozymes in 11 benign cystic teratomas of the human female ovary were compared with normal tissue of the same case.
openaire +2 more sources
Frontiers in Genetics, 2020 Most species of Santalales (the sandalwood order) are hemiparasites, including both facultative and obligate hemiparasites. Despite its rich diversity, only a small fraction of the species in the sandalwood order have sequenced plastomes.
Xiaorong Guo +8 more
doaj +1 more source
Parallel loss-of-function at the RPM1 bacterial resistance locus in Arabidopsis thaliana [PDF]
, 2012 Dimorphism at the Resistance to Pseudomonas syringae pv. maculicola 1 (RPM1) locus is well documented in natural populations of Arabidopsis thaliana and has been portrayed as a long-term balanced polymorphism. The haplotype from resistant plants contains
Grant, Murray +11 more
core +1 more source
Insects, 2023 Expanding on previous efforts to survey the visual opsin repertoires of the Hemiptera, this study confirms that homologs of the UV- and LW-opsin subfamilies are conserved in all Hemiptera, while the B-opsin subfamily is missing from the Heteroptera and ...
Markus Friedrich
doaj +1 more source
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]
, 2010 Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
S Eyre +21 more
core +1 more source