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Cancer research, 1992
The significance of the retinoblastoma gene (RB) in the development of human breast cancer remains unclear. In the present study, loss of heterozygosity (LOH) in RB was found in 26% of 90 informative primary breast tumors and was correlated to DNA nondiploidy, a high S-phase fraction, and LOH at chromosome 17p13.3.
A, Borg +4 more
openaire +1 more source
The significance of the retinoblastoma gene (RB) in the development of human breast cancer remains unclear. In the present study, loss of heterozygosity (LOH) in RB was found in 26% of 90 informative primary breast tumors and was correlated to DNA nondiploidy, a high S-phase fraction, and LOH at chromosome 17p13.3.
A, Borg +4 more
openaire +1 more source
Advances in gene therapy hold promise for treating hereditary hearing loss
Molecular Therapy, 2023Yilai Shu, Luoying Jiang
exaly
Current Advances in Adeno-Associated Virus-Mediated Gene Therapy to Prevent Acquired Hearing Loss
JARO - Journal of the Association for Research in Otolaryngology, 2022Kumar Sambamurti, Su-Hua Sha
exaly
Microsporidia: Eukaryotic Intracellular Parasites Shaped by Gene Loss and Horizontal Gene Transfers
Annual Review of Microbiology, 2015Nicolas Corrádi
exaly
Rates and patterns of gene duplication and loss in the human genome
Proceedings of the Royal Society B: Biological Sciences, 2005James Cotton, Roderic Page
exaly
Disentangling the effects of selection and loss bias on gene dynamics
Proceedings of the National Academy of Sciences of the United States of America, 2017Mikhail Katsnelson +2 more
exaly