Results 101 to 110 of about 542,125 (315)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
First century of chicken gene study and mapping – a look back and forward
, 2004 Chicken gene inheritance analysis, started one century ago, had led to the development of the classical genetic map. Efforts and legacy of the previous geneticists' generations are not forgotten and constitute the fundamentals of contemporary genome ...
Romanov, Michael N +2 more
core +1 more source
Editorial: Genomics and disease resistance in wheat and maize
Frontiers in Plant Science, 2022 Cheng Liu +6 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Mapping of the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) to chicken chromosome 3
, 2001 Source/description: The chicken luteinizing hormone/choriogonadotropin receptor gene has been cloned and sequenced. To produce markers for linkage mapping genomic DNA sequence from exon 7 to exon 9 including the intervening introns and exon was cloned ...
Romanov, MN +17 more
core +1 more source
Identification and gene mapping of a novel rice albino lethal abl25 mutant
上海师范大学学报. 自然科学版, 2014 A novel rice albino lethal mutant,abl25,was obtained from 60 Coγ-ray radiation mutant pool of japonica rice Jiahua No.1.The mutant displayed albino-phenotype from germination to four-leaf-old seedings,thereafter,exhibited an albino lethal phenotype ...
ZHU Huanhuan +5 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Statistical Topics in Disease Gene Mapping
, 2003 Efforts in disease gene mapping have achieved a great deal of success in mendelain diseases, but made slower progress in common disease studies because of their complexity.
Meng, Zhaoling
core