Results 1 to 10 of about 13,573 (129)

Computational Screening of Approved Drugs for Inhibition of the Antibiotic Resistance Gene mecA in Methicillin-Resistant Staphylococcus aureus (MRSA) Strains [PDF]

BioTech, 2023
Antibiotic resistance is a critical problem that results in a high morbidity and mortality rate. The process of discovering new chemotherapy and antibiotics is challenging, expensive, and time-consuming, with only a few getting approved for clinical use.
Benson Otarigho, Mofolusho O. Falade
doaj   +2 more sources

Antibacterial Effect of the In Vitro Interaction Between Clotrimazole and Chlorhexidine Against Staphylococcus pseudintermedius With Known Resistance Patterns Isolated From Canine Pyoderma. [PDF]

Vet Med Sci
The 2:1 chlorhexidine–clotrimazole combination demonstrated enhanced antibacterial activity against canine Staphylococcus pseudintermedius isolates, including resistant strains. Reduced MIC values, predominantly additive interactions and absence of antagonism support its use as a promising topical strategy for canine pyoderma management.
Gallegos-Torres B, Alfonseca-Silva E, Ledesma-Carrasco C, Aquino-Díaz I.   +3 more
europepmc   +2 more sources

A preliminary study of mecA gene expression and methicillin resistance in staphylococci isolated from the human oral cavity

Sri Lankan Journal of Infectious Diseases, 2019
Introduction: Staphylococci are common human commensals that acquire methicillin resistance via the mecA gene. Methicillin resistance in staphylococci from various clinical sources has been assessed using cefoxitin disc diffusion test (CDDT) and PCR ...
WMDA Wijesundara, RGSC Rajapakse, JAMA Jayatilake, JAMS Jayatilake   +3 more
doaj   +3 more sources

Genetic Diversity and Epidemiological Overlap of Staphylococcus aureus at the Animal-Food-Environment-Human Interface Within a One Health Framework. [PDF]

Microbiologyopen
Integrating farm‐to‐fork and clinical surveillance, this study reveals distinct SCCmec distributions alongside shared spa types across human, animal, and food interfaces. The results of genetic diversity and epidemiological overlap underscore the critical need for coordinated One Health surveillance to monitor multi‐sectoral Staphylococcus aureus ...
Sagiroglu P, Gundog DA, Gungor C, Koskeroglu K, Atalay MA, Dishan A, Ucar Y, Akcay A, Disli HB, Hizlisoy H, Barel M, Kececi T, Onmaz NE.   +12 more
europepmc   +2 more sources

Molecular Diagnostics for WHO Priority Bacterial Pathogens: A Bibliometric Mapping of Diagnostic Platforms, Resistance Markers, and Antimicrobial Resistance Research Trends. [PDF]

Microbiologyopen
This bibliometric mapping of 1746 publications (2000–2025) charts molecular diagnostics for WHO priority bacterial pathogens across platforms, targets, and resistance markers. Conventional PCR/NAAT and whole‐genome sequencing emerge as complementary core platforms, and the field evolves from targeted pathogen detection into an AMR‐centered ...
Ünlü S.
europepmc   +2 more sources

Screening for mecA and mecC Gene Carriage among Clinical Isolates of Methicillin Resistant Staphylococcus aureus at a Tertiary Care Hospital: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Staphylococcus aureus (S. aureus) has emerged as one of the most important human pathogen, and has been a leading cause of hospital and community acquired infections. Methicillin-Resistant Staphylococcus aureus (MRSA) carrying the mecA gene
Rakshita Ramesh, Deepa Sinha, R Ambica, GB Shantala   +3 more
doaj   +1 more source

Methods of detection and typing of methicillin resistant Staphylococcus aureus isolated from animals [PDF]

Veterinarski Glasnik, 2014
In this work there was evaluated the method of detection of methicillin resistant Staphylococcus aureus (MRSA) by using two molecular and three phenotypic tests in investigation procedure of 70 strains of S.aureus isolated from animals.
Radosavljević V., Žutić Jadranka, Pavlović Ljiljana, Bošković Tamara, Radanović O., Žutić M.   +5 more
doaj   +1 more source

Molecular and phylogenetic study of Staphylococcus aureus isolated from human and cattle of Al-Qadisiyah Governorate, Iraq [PDF]

Veterinary World, 2019
Aim: This study was designed to detect the prevalence of Staphylococcus aureus, to estimate the frequency of methicillin resistance gene (mecA), femA (specific gene for S.
Ahmed Jasim Neamah, Hayder Naji Ayyez, Saba Falah Klaif, Yahia Ismail Khudhair, Muthanna Hadi Hussain   +4 more
doaj   +1 more source

Phenotypic and Genotypic Characterization of Methicillin Resistance in Staphylococci Isolated from an Egyptian University Hospital

Pathogens, 2023
Methicillin-resistant in Staphylococci is a serious public health issue. It is mostly encoded by the mecA gene. The mecC gene is a new mecA analog responsible for resistance to methicillin in some Staphylococcal clinical isolates. This mecC gene is still
Marwa A. Abdelwahab, Wesam H. Amer, Dalia Elsharawy, Reham M. Elkolaly, Rehab Abd El Fattah Helal, Dina Ahmed El Malla, Yomna G. Elfeky, Hebatallah A. Bedair, Rania S. Amer, Marwa E. Abd-Elmonsef, Marwa S. Taha   +10 more
doaj   +1 more source

Comparative Analysis of mecA and nuc Gene Sequences of Staphylococcus aureus Strains Isolated from Human Urine Samples

Journal of Pure and Applied Microbiology, 2017
In the present study twenty five human urine samples of hospital patients were screened for Staphylococcus aureus. Twenty percent of the samples were positive for Staphylococcus aureus as yellow colonies were observed aerobically on mannitol salt agar ...
Ann Maxton, Sam A. Masih, Shashi B. Bailey, G.D. Ram, Satendra Singh   +4 more
doaj   +1 more source