Results 11 to 20 of about 13,121 (177)
Computational Screening of Approved Drugs for Inhibition of the Antibiotic Resistance Gene mecA in Methicillin-Resistant Staphylococcus aureus (MRSA) Strains [PDF]
BioTech, 2023 Antibiotic resistance is a critical problem that results in a high morbidity and mortality rate. The process of discovering new chemotherapy and antibiotics is challenging, expensive, and time-consuming, with only a few getting approved for clinical use.
Benson Otarigho, Mofolusho O. Falade
doaj +2 more sources
RPA Combined With CRISPR/Cas12a for Rapid and Ultrasensitive Detection Dual‐Gene of Methicillin‐Resistant Staphylococcus aureus (MRSA) [PDF]
Journal of Molecular Recognition, Volume 39, Issue 3, May 2026.ABSTRACT The increasing issue of infections caused by methicillin‐resistant Staphylococcus aureus (MRSA) necessitates rapid and reliable diagnostic methods. While existing RPA‐CRISPR/Cas12a platforms have demonstrated potential for MRSA detection, most rely on single‐gene targets or require multiple Cas enzymes.
Lei Chen +3 more
wiley +2 more sources
spa Typing and Antibiotic Resistance Profiles of Methicillin‐Resistant Staphylococcus aureus Isolates From Broilers in Ilam, Iran [PDF]
Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.This study characterized MRSA in broilers in Ilam, Iran. Of 200 swabs, 107 Staphylococcus aureus isolates were confirmed by femA PCR, of which 9 (8.41%) were MRSA (mecA‐positive). spa typing revealed five distinct types, with t011 dominant (40%). Novel types for Iran included t304, t567 and t1184.
Zeinab Alimadad +2 more
wiley +2 more sources
Wastewater‐Based Assessment of Antimicrobial Resistance and Bacterial Communities in Urban and Rural Areas in the Province of Trento (Italy) [PDF]
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Wastewater from urban and rural areas was analyzed to investigate antimicrobial‐resistant bacteria and resistance genes. ESBL‐Escherichia coli and genes coding for clinically relevant resistances, namely, those to macrolides, carbapenems, and vancomycin, were higher in urban than in rural areas.
Maya Petricciuolo +7 more
wiley +2 more sources
SNP Scanning in mecA Gene for Methicillin-Resistant Staphylococcus aureus.
Iranian journal of biotechnology, 2020 Staphylococcus aureus (SA) is known as an important human pathogen, which is responsible for many cases of both hospital and community-acquired infections all over the world. Studying on drug resistance is regarded as an important prevention strategy regarding these types of infections.The current study is aimed to assess the association between the ...
Salehi, Mitra +3 more
openaire +2 more sources
Genetic organization of mecA and mecA-regulatory genes in epidemic methicillin-resistant Staphylococcus aureus from Australia and England [PDF]
Journal of Antimicrobial Chemotherapy, 2002 The mecA gene that encodes methicillin resistance in Staphylococcus aureus may be regulated by the mecR1 and mecI genes, and this region has been referred to as the mec complex. An analysis of these regulatory genes in 35 epidemic methicillin-resistant S.
Lim, T.T., Coombs, G.W., Grubb, W.B.
openaire +2 more sources
Systemic Analysis of the mecA Gene Using a Bioinformatics Tool [PDF]
Open Forum Infectious Diseases, 2017 BACKGROUND: The mecA gene, carried by methicillin-resistant Staphylococcus aureus (MRSA), allows the bacterium to promotes bacterial resistance to antibiotics such as methicillin, penicillin, and other penicillin-like antibiotics. Our objectives are to use a bioinformatics tool to analyze the sequence of the mecA gene, which is spread on the SCCmec ...
Tsai, Shin-Yi +7 more
openaire +1 more source
Impairments of mecA gene detection in bovine Staphylococcus spp. [PDF]
Brazilian Journal of Microbiology, 2014 Staphylococcus aureus antimicrobial resistance, especially to beta-lactams, favors treatment failures and its persistence in herd environment. This work aimed to develop a more specific primer for mecA gene detection based on the comparison of the conserved regions from distinct host origins and also investigated the presence of homologue mecA(LGA251 ...
Melo, Dayanne Araújo de +6 more
openaire +4 more sources
Pathogens, 2023 Methicillin-resistant in Staphylococci is a serious public health issue. It is mostly encoded by the mecA gene. The mecC gene is a new mecA analog responsible for resistance to methicillin in some Staphylococcal clinical isolates. This mecC gene is still
Marwa A. Abdelwahab +10 more
doaj +1 more source
Journal of Pure and Applied Microbiology, 2017 In the present study twenty five human urine samples of hospital patients were screened for Staphylococcus aureus. Twenty percent of the samples were positive for Staphylococcus aureus as yellow colonies were observed aerobically on mannitol salt agar ...
Ann Maxton +4 more
doaj +1 more source