Results 21 to 30 of about 13,121 (177)
Evidence for the evolutionary steps leading to mecA-mediated β-lactam resistance in staphylococci. [PDF]
PLoS Genetics, 2017 The epidemiologically most important mechanism of antibiotic resistance in Staphylococcus aureus is associated with mecA-an acquired gene encoding an extra penicillin-binding protein (PBP2a) with low affinity to virtually all β-lactams.
Joana Rolo +12 more
doaj +1 more source
Ceftaroline resistance in Staphylococcus pseudintermedius gene mecA carriers [PDF]
Pesquisa Veterinária Brasileira, 2018 ABSTRACT: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) being a constant concern, ceftaroline fosamil has been recently approved as a new cephalosporin, active against MRSA, for use in humans; only rare cases of resistance have been reported till date.
Scherer, Carolina B. +4 more
openaire +4 more sources
International Journal of Microbiology, 2023 Background. Staphylococcus aureus (S. aureus) causes different types of human infections and can develop resistance to many antibiotics. There is a scarcity of data on the mecA gene and multidrug-resistant (MDR) strain distribution of this organism in ...
Feleke Moges +8 more
doaj +1 more source
mecA Gene Is Widely Disseminated in Staphylococcus aureus Population [PDF]
Journal of Clinical Microbiology, 2002 ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most important causes of hospital infections worldwide. High-level resistance to methicillin is caused by the mecA gene, which encodes an alternative penicillin-binding protein, PBP 2a. To determine the clonal
C L C, Wielders +4 more
openaire +2 more sources
Methicillin-resistance in Staphylococcus aureus is not affected by the overexpression in trans of the mecA gene repressor: a surprising observation. [PDF]
PLoS ONE, 2011 Methicillin-resistant Staphylococcus aureus (MRSA) is intrinsically cross-resistant to virtually all β-lactam antibiotics. The central determinant for the MRSA phenotype is the mecA gene, whose transcriptional control may be mediated by a repressor (mecI)
Duarte C Oliveira +1 more
doaj +1 more source
Vancomycin-induced deletion of the methicillin resistance gene mecA in Staphylococcus aureus [PDF]
Journal of Antimicrobial Chemotherapy, 2004 To elucidate factors that contribute to the development of vancomycin resistance in methicillin-resistant Staphylococcus aureus (MRSA).Forty-nine MRSA isolates were subjected to passage selection with vancomycin to isolate mutants with reduced susceptibility to vancomycin.
Adhikari, Rajan P. +5 more
openaire +3 more sources
MRSA/MSSA causing infections: prevalence of mecA gene
European Journal of Public Health, 2020 Abstract Introduction Staphylococcus aureus is part of the human flora, present in the skin and mucous membranes but can become pathogenic, causing a wide spectrum of infections that were initially treated with penicillin. However, were observed some strains with resistance to this antibiotic and, therefore was developed a new antibiotic,
N Osório +5 more
openaire +1 more source
Identification of MRSA(methicillin resistant Staphylococcus aureus) by mecA gene
Al-Salam Journal for Medical Science, 2022 Staphylococcus aureus is a bacterium that may be found in the skin and upper respiratory system. Although S.aureus is a normal flora, it has evolved into an opportunistic pathogen that causes numerous infections that are difficult to cure due to the presence of virulence genes.
Marwa raad +2 more
openaire +2 more sources
Journal of Nepal Health Research Council, 2023 Background: The emergence of Methicillin-resistant Staphylococcus aureus and its ability to confer cross-resistance to macrolide-lincosamide-streptogramin B has complicated the treatment against it.
Dudha Raj Malla Thakuri +7 more
doaj +1 more source
The Iraqi Journal of Medical Sciences, 2016 Background: Methicillin-resistant Staphylococcus aureus is a major cause of serious nosocomial infections and it is very important to have a reliable test to detect these bacteria.
Rafeef Y. Rasheed, Ahmed S. Abdulamir
doaj +4 more sources