Results 111 to 120 of about 7,142,455 (272)

Automatic, context-specific generation of Gene Ontology slims

open access: yesBMC Bioinformatics, 2010
Background The use of ontologies to control vocabulary and structure annotation has added value to genome-scale data, and contributed to the capture and re-use of knowledge across research domains.
Sehgal Muhammad   +2 more
doaj   +1 more source

Gene Ontology Enrichment Improves Performances of Functional Similarity of Genes

open access: yesScientific Reports, 2018
There exists a plethora of measures to evaluate functional similarity (FS) between genes, which is a widely used in many bioinformatics applications including detecting molecular pathways, identifying co-expressed genes, predicting protein-protein ...
Wenting Liu   +2 more
semanticscholar   +1 more source

Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology

open access: yesCirculation Genomic and Precision Medicine, 2018
Background: A systems biology approach to cardiac physiology requires a comprehensive representation of how coordinated processes operate in the heart, as well as the ability to interpret relevant transcriptomic and proteomic experiments.
R. Lovering   +19 more
semanticscholar   +1 more source

The Gene Ontology Resource: 20 years and still GOing strong. [PDF]

open access: yes, 2019
The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products.
Consortium, Gene Ontology
core   +1 more source

The development of non-coding RNA ontology [PDF]

open access: yes, 2016
Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data ...
Blake, Judith   +15 more
core   +1 more source

FFPred 3: feature-based function prediction for all Gene Ontology domains

open access: yesScientific Reports, 2016
Predicting protein function has been a major goal of bioinformatics for several decades, and it has gained fresh momentum thanks to recent community-wide blind tests aimed at benchmarking available tools on a genomic scale.
Domenico Cozzetto   +3 more
semanticscholar   +1 more source

The effects of shared information on semantic calculations in the gene ontology

open access: yesComputational and Structural Biotechnology Journal, 2017
The structured vocabulary that describes gene function, the gene ontology (GO), serves as a powerful tool in biological research. One application of GO in computational biology calculates semantic similarity between two concepts to make inferences about ...
Paul W. Bible   +4 more
doaj   +1 more source

Evaluating Computational Gene Ontology Annotations [PDF]

open access: yes, 2016
ISBN:978-1-4939-3743 ...
Richard J. Roberts   +4 more
openaire   +4 more sources

NaviGO: interactive tool for visualization and functional similarity and coherence analysis with gene ontology

open access: yesBMC Bioinformatics, 2017
The number of genomics and proteomics experiments is growing rapidly, producing an ever-increasing amount of data that are awaiting functional interpretation.
Qing Wei   +4 more
semanticscholar   +1 more source

SORGOdb: Superoxide Reductase Gene Ontology curated DataBase

open access: yesBMC Microbiology, 2011
Background Superoxide reductases (SOR) catalyse the reduction of superoxide anions to hydrogen peroxide and are involved in the oxidative stress defences of anaerobic and facultative anaerobic organisms.
Salbert Gilles   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy