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Methods for Gene Ontology Annotation [PDF]
, 2007 The Gene Ontology (GO) is an established dynamic and structured vocabulary that has been successfully used in gene and protein annotation. Designed by biologists to improve data integration, GO attempts to replace the multiple nomenclatures used by specialised and large biological knowledgebases.
Emily Dimmer +3 more
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Application of Gene Ontology to Gene Identification
2011Candidate gene identification deals with associating genes to underlying biological phenomena, such as diseases and specific disorders. It has been shown that classes of diseases with similar phenotypes are caused by functionally related genes. Currently, a fair amount of knowledge about the functional characterization can be found across several ...
Bruno Tavares +4 more
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The ontology of the gene ontology.
AMIA ... Annual Symposium proceedings. AMIA Symposium, 2004The rapidly increasing wealth of genomic data has driven the development of tools to assist in the task of representing and processing information about genes, their products and their functions. One of the most important of these tools is the Gene Ontology (GO), which is being developed in tandem with work on a variety of bioinformatics databases.
Barry, Smith +2 more
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On ontologies for biologists: the Gene Ontology--untangling the web.
Novartis Foundation symposium, 2002The mantra of the 'post-genomic' era is 'gene function'. Yet surprisingly little attention has been given to how functional and other information concerning genes is to be captured, made accessible to biologists or structured in a computable form. The aim of the Gene Ontology (GO) Consortium is to provide a framework for both the description and the ...
Michael Ashburner, Suzanna E. Lewis
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Gene multifunctionality scoring using gene ontology
Journal of Bioinformatics and Computational Biology, 2018Multifunctional genes are important genes because of their essential roles in human cells. Studying and analyzing multifunctional genes can help understand disease mechanisms and drug discovery. We propose a computational method for scoring gene multifunctionality based on functional annotations of the target gene from the Gene Ontology. The method is
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Generative adversarial learning for optimizing ontology alignment
Expert Systems, 2023Xingsi Xue
exaly
Using NSGA‐III for optimising biomedical ontology alignment
CAAI Transactions on Intelligence Technology, 2019Jiawei Lu, Xingsi Xue, Hong Quoc Nguyen
exaly