Ontologizing gene-expression microarray data: characterizing clusters with Gene Ontology [PDF]
Bioinformatics, 2004 Abstract Summary: An XML-based Java application is described that provides a function-oriented overview of the results of cluster analysis of gene-expression microarray data based on Gene Ontology terms and associations. The application generates one HTML page with listings of the frequencies of explicit and implicit Gene Ontology ...
Peter N. Robinson +3 more
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Gene Expression Analysis to Mine Highly Relevant Gene Data in Chronic Diseases and Annotating its GO Terms [PDF]
EAI Endorsed Transactions on Energy Web, 2020 Gene Expression Analysis seeks to find the highly expressive genes from a highly dimensional Microarray disease gene Database by using some statistical gene selection approaches based on supervised or unsupervised learning.
J. Bell, S. Vigila
doaj +1 more source
Exploring autophagy with Gene Ontology [PDF]
Autophagy, 2018 Autophagy is a fundamental cellular process that is well conserved among eukaryotes. It is one of the strategies that cells use to catabolize substances in a controlled way. Autophagy is used for recycling cellular components, responding to cellular stresses and ridding cells of foreign material.
Paul Denny +5 more
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The Gene Ontology Resource: 20 years and still GOing strong. [PDF]
, 2019 The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products.
Consortium, Gene Ontology
core +7 more sources
Cross-Ontology multi-level association rule mining in the Gene Ontology. [PDF]
PLoS ONE, 2012 The Gene Ontology (GO) has become the internationally accepted standard for representing function, process, and location aspects of gene products. The wealth of GO annotation data provides a valuable source of implicit knowledge of relationships among ...
Prashanti Manda +4 more
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The Gene Ontology of eukaryotic cilia and flagella [PDF]
Cilia, 2017 Recent research into ciliary structure and function provides important insights into inherited diseases termed ciliopathies and other cilia-related disorders. This wealth of knowledge needs to be translated into a computational representation to be fully exploitable by the research community.
Jane Lomax +10 more
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Mining the Gene Wiki for functional genomic knowledge
BMC Genomics, 2011 Background Ontology-based gene annotations are important tools for organizing and analyzing genome-scale biological data. Collecting these annotations is a valuable but costly endeavor.
Good Benjamin M +4 more
doaj +1 more source
GOexpress: an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data [PDF]
, 2016 Background: Identification of gene expression profiles that differentiate experimental groups is critical for discovery and analysis of key molecular pathways and also for selection of robust diagnostic or prognostic biomarkers.
Gordon, SV +7 more
core +4 more sources
Formalization of gene regulation knowledge using ontologies and gene ontology causal activity models
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2021 Gene regulation computational research requires handling and integrating large amounts of heterogeneous data. The Gene Ontology has demonstrated that ontologies play a fundamental role in biological data interoperability and integration. Ontologies help to express data and knowledge in a machine processable way, which enables complex querying and ...
Cortés, BJ +9 more
openaire +8 more sources
Construction of ontology augmented networks for protein complex prediction.
PLoS ONE, 2013 Protein complexes are of great importance in understanding the principles of cellular organization and function. The increase in available protein-protein interaction data, gene ontology and other resources make it possible to develop computational ...
Yijia Zhang +3 more
doaj +1 more source