Results 41 to 50 of about 426,507 (329)
Functional-network-based gene set analysis using gene-ontology. [PDF]
PLoS ONE, 2013 To account for the functional non-equivalence among a set of genes within a biological pathway when performing gene set analysis, we introduce GOGANPA, a network-based gene set analysis method, which up-weights genes with functions relevant to the gene ...
Billy Chang, Rafal Kustra, Weidong Tian
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A Bayesian Hierarchical Model to Derive Novel Gene Networks from Gene Ontology Fingerprints [PDF]
, 2009 We developed a Bayesian hierarchical model to identify gene networks based on the similarity score generated from comparing the gene ontology fingerprints of gene pairs.
Andrew Lawson +3 more
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Improvements to cardiovascular Gene Ontology
Atherosclerosis, 2009 Gene Ontology (GO) provides a controlled vocabulary to describe the attributes of genes and gene products in any organism. Although one might initially wonder what relevance a 'controlled vocabulary' might have for cardiovascular science, such a resource is proving highly useful for researchers investigating complex cardiovascular disease phenotypes as
Ruth C. Lovering +2 more
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Disjunctive shared information between ontology concepts: application to Gene Ontology
Journal of Biomedical Semantics, 2011 Background The large-scale effort in developing, maintaining and making biomedical ontologies available motivates the application of similarity measures to compare ontology concepts or, by extension, the entities described therein.
Couto Francisco M, Silva Mário J
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Gene function prediction based on the Gene Ontology hierarchical structure. [PDF]
PLoS ONE, 2014 The information of the Gene Ontology annotation is helpful in the explanation of life science phenomena, and can provide great support for the research of the biomedical field.
Liangxi Cheng +4 more
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Onion Extract on Cell Gene Expression Profile: a System Biology Approach [PDF]
Research Journal of Pharmacognosy, 2023 Background and objectives: Widespread consuming of onion as a nutrient in the world implies more investigations about useful and harmful aspects of this common supplementary food.
Babak Arjmand +5 more
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Length bias correction in gene ontology enrichment analysis using logistic regression. [PDF]
PLoS ONE, 2012 When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called "length bias", will influence
Gu Mi +4 more
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Controlled vocabularies in bioinformatics: A case study in the Gene Ontology [PDF]
, 2004 The automatic integration of information resources in the life sciences is one of the most challenging goals facing biomedical informatics today. Controlled vocabularies have played an important role in realizing this goal, by making it possible to draw ...
Anand Kumar +11 more
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CirGO: an alternative circular way of visualising gene ontology terms
BMC Bioinformatics, 2019 Background Prioritisation of gene ontology terms from differential gene expression analyses in a two-dimensional format remains a challenge with exponentially growing data volumes.
Irina Kuznetsova +4 more
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The Gene Ontology Handbook [PDF]
, 2017 #TheGeneOntologyHandbook ; #BiologicalKnowledge ; This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made ...
Dessimoz, Christophe, Škunca, Nives
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