Results 91 to 100 of about 3,153,117 (306)
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
VDBP Gene Polymorphism in COPD
Chronic obstructive pulmonary disease (COPD) is a disease which genetic and environmental factors play an important role in COPD development. VDBP (Vitamin D Binding Protein ) gene might be responsible for COPD development. The purpose of this study to investigate the possible effect of VDBP on progression of COPD.
BAYKARA, ONUR +3 more
openaire +3 more sources
Association between xenobiotic gene polymorphisms and non-Hodgkin's lymphoma risk
The last four decades have seen a significant increase in the incidence of non-Hodgkin's lymphoma (NHL) as a possible result of increasing environmental carcinogen exposure, particularly pesticides and solvents.
Lincz, Lisa +5 more
core +1 more source
From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss +9 more
wiley +1 more source
Gene polymorphisms as markers of disease susceptibility [PDF]
The most widespread diseases of modern man have a polygenic basis, including genetic predisposition and factors in the external environment. Such is the case with cardiovascular disease, malignancy, diabetes and so on.
Novaković Ivana +3 more
doaj
The aim of this study was to determine the genotype distributions of calcitonin related polypeptide alpha (CALCA) gene polymorphisms according to the plasma total homocysteine levels in ischemic stroke patients and patient subtypes selected from Trakya ...
Nevra Alkanli +7 more
doaj +1 more source
Analysis of 3 common polymorphisms in the KCNK18 gene in an Australian migraine case-control cohort [PDF]
Migraine is a common neurological disorder characterised by temporary disabling attacks of severe head pain and associated disturbances. There is significant evidence to suggest a genetic aetiology to the disease however few causal mutations have been ...
Taylor, M +15 more
core +1 more source
Objective We examined associations of posttraumatic stress disorder (PTSD) and other mental health disorders (OMH) with rheumatoid arthritis (RA), accounting for effects of smoking. Methods We conducted a matched case‐control study, identifying incident RA cases and controls using national Veterans Health Administration data (2006–2019).
Kelsey Coziahr +15 more
wiley +1 more source
The aim of this work was to study the relationship between Pro12Ala polymorphisms of the PPARG gene and Gly482Ser of the PPARGC1A gene with metabolic syndrome in individuals with VD.
L. B. Masnavieva +4 more
doaj +1 more source
Interleukin-1β-gene polymorphisms in preeclamptic Egyptian women
Aim of work: To investigate the relationship between IL-1β -31C/T (rs 1143627) and -11T/C (rs 16944) gene polymorphisms and preeclampsia. Patients and methods: Polymorphisms at -31C/T and -511T/C of IL-1β were genotyped using polymerase chain reaction ...
Aml S. Nasr +4 more
doaj +1 more source

