Results 81 to 90 of about 859,450 (301)

NEMATODES OF THE GENUS SETARIA VIBORG, 1795 (FILARIINA: SETARIDAE), THE PARASITES OF THE ANIMALS OF UZBEKISTAN: MORPHOLOGICAL AND MOLECULAR APPROACHES TO THEIR DIFFERENTIATION

open access: yesРоссийский паразитологический журнал, 2016
Objective of research:   The purpose of  the  research is to study the species diversity of nematodes of the genus  Setaria, the  character of their distribution among the animals of Uzbekistan and morphologic  and genetic approaches to their ...
D. A. Azimov   +6 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Overexpression of beta-carotene hydroxylase enhances stress tolerance in Arabidopsis [PDF]

open access: yes, 2002
Plant stress caused by extreme environmental conditions is already a principal reason for yield reduction in crops. The threat of global environment change makes it increasingly important to generate crop plants that will withstand such conditions ...
Davison, P.A., Horton, P., Hunter, C.N.
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Gene cloning - techniques and strategies [PDF]

open access: yes, 2003
Genetic information is coded in DNA found in the nucleus and mitochondria of animal cells and chloroplast of plant cells. The flow of genetic information from DNA to RNA and subsequently to polypeptides or proteins forms the central dogma of molecular ...
Jayasankar, P
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Methicillin-resistant Staphylococcus aureus (MRSA) associated with mastitis among water buffaloes in the Philippines

open access: yesHeliyon, 2020
Methicillin-resistant Staphylococcus aureus (MRSA) from dairy animals could pose a public health concern in the population. The study was designed to determine the prevalence of S.
Alona T. Badua   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS)

open access: yesРоссийский паразитологический журнал, 2016
The anticoagulant effect of salivary secretion of ticks Argas persicus was studied. The experiments were conducted on aorta preparations isolated from the chest of white outbread rats.
A. U. Mirzayeva   +2 more
doaj  

Genome mapping of quantitative trait loci (QTL) controlling domestication traits of intermediate wheatgrass (Thinopyrum intermedium). [PDF]

open access: yes, 2019
Allohexaploid (2n = 6x = 42) intermediate wheatgrass (Thinopyrum intermedium), abbreviated IWG, is an outcrossing perennial grass belonging to the tertiary gene pool of wheat.
Anderson, James   +13 more
core  

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