Results 61 to 70 of about 319,651 (293)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Diversidad de faseolinas en frijol común cultivado del Caribe Phaseolin diversity in cultivated common bean from the Caribbean

Acta Agronómica, 2007
Se evaluó el tipo de faseolina en 180 accesiones cultivadas de Phaseolus vulgaris del Caribe de la colección del Centro Internacional de Agricultura Tropical (CIAT).
Matthew W. Blair, Wilfredo Pantoja D, Rigoberto Hidalgo   +2 more
doaj  

Microsatellite-Based Genetic Structure and Diversity of Local Arabian Sheep Breeds

Frontiers in Genetics, 2018
The genetic diversity of the sheep breeds in the Arab countries might be considered to be a mirror of the ecology of the region. In this study, the genetic structure and diversity of sheep breeds from Saudi Arabia (Harri, Najdi, Naemi, Arb, and Rufidi ...
Raed M. Al-Atiyat, Raed M. Al-Atiyat, Riyadh S. Aljumaah, Mohammad A. Alshaikh, Alaeldein M. Abudabos   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The efficiency of AFLP and SSR markers in genetic diversity estimation and gene pool classification of common bean (Phaseolus vulgaris L.)

Acta Agriculturae Slovenica, 2008
The present work was conducted to evaluate AFLP (Amplified Fragment Length Polymorphism) and SSR (Simple Sequence Repeat) marker systems for their ability to detect genetic diversity within a set of 29 common bean accessions spanning both the Andean and ...
Marko MARAS, Jelka ŠUŠTAR-VOZLIČ, Branka JAVORNIK, Vladimir MEGLIČ   +3 more
doaj   +1 more source

Effect of pooling samples on the efficiency of comparative studies using microarrays

, 2005
Many biomedical experiments are carried out by pooling individual biological samples. However, pooling samples can potentially hide biological variance and give false confidence concerning the data significance.
Agrawal, Churchill, Gastwirth, Jin, Kendziorski, Peng, Pounds, S.-D. Zhang, T. W. Gant   +8 more
core   +1 more source

Holobiont Evolution: Mathematical Model with Vertical vs. Horizontal Microbiome Transmission [PDF]

, 2020
A holobiont is a composite organism consisting of a host together with its microbiome, such as a coral with its zooxanthellae. To explain the often intimate integration between hosts and their microbiomes, some investigators contend that selection ...
Roughgarden, Joan
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Chicken as a carrier of emerging virulent Helicobacter species: a potential zoonotic risk

Gut Pathogens
Background The research scope regarding Helicobacter species in chickens, other than H. pullorum, is largely overlooked. This study aimed to investigate the prevalence of emerging Helicobacter species in chickens and the occurrence of the virulence gene ...
Ahmed Samir, Hala M. Zaher
doaj   +1 more source

Screening of Arabidopsis mutants for functional genomic studies [PDF]

, 2008
Eight photosynthetic Arabidopsis mutants were screened for co-segregation of a photosynthetic phenotype with the T-DNA insertion. These mutants were selected from 80 photosynthetic mutants with genetic background of Columbia-0.
Ahmad, Rashid, Altaf, Javaria, Awan, Faisal Saeed, Khan, Asif Ali, Khan, Iftikhar Ahmad, Leister, Dario, Schneider, Anja   +6 more
core   +1 more source