Results 1 to 10 of about 131,348 (136)

Effects of the tat and nef gene products of human immunodeficiency virus type 1 (HIV-1) on transcription controlled by the HIV-1 long terminal repeat and on cell growth in macrophages [PDF]

Journal of Virology, 1993
The RAW264 murine macrophage cell line was used as a model to examine the role of the tat and nef gene products in the transcription regulation of the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) in macrophages. Contrary to claims that the activity of the HIV-1 LTR responds poorly in rodent cells to trans activation by the ...
Murphy, Kathleen M., Sweet, Matthew J., Ross, Ian L., Hume, David A.   +3 more
openaire   +7 more sources

TAT gene polymorphism and its relationship with production traits in Muscovy ducks (Cairina Moschata)

Poultry Science, 2023
In a previous study, the laying pattern of Muscovy duck was explored by macro-fitting the laying curve of Muscovy duck, and transcriptome sequencing technique of the ovarian tissues was used to screen the egg-related gene "TAT." Moreover, recent results have shown that TAT is expressed in organs such as oviduct, ovary, and testis. The objective of this
Xing Ju, Zhijun Wang, Danfeng Cai, Haiping Xu, Semiu Folaniyi Bello, Siyu Zhang, Weijian Zhu, Congliang Ji, Qinghua Nie   +8 more
openaire   +3 more sources

Evaluating the genotoxicity of salinity stress and secondary products gene manipulation in lime, Citrus aurantifolia, plants

Frontiers in Plant Science, 2023
Salinity is a significant abiotic stress that has a profound effect on growth, the content of secondary products, and the genotoxicity of cells. Lime, Citrus aurantifolia, is a popular plant belonging to the family Rutaceae.
Hadeer Darwish, Hadeer Darwish, Ghaida S. Al-Osaimi, Najla Amin T. Al Kashgry, Hana Sonbol, Aisha A. M. Alayafi, Nadiyah M. Alabdallah, Nadiyah M. Alabdallah, Abdulrahman Al-Humaid, Nadi Awad Al-Harbi, Salem Mesfir Al-Qahtani, Zahid Khorshid Abbas, Doaa Bahaa Eldin Darwish, Doaa Bahaa Eldin Darwish, Mohamed F. M. Ibrahim, Ahmed Noureldeen, Ahmed Noureldeen   +16 more
doaj   +1 more source

T-cell responses targeting HIV Nef uniquely correlate with infected cell frequencies after long-term antiretroviral therapy. [PDF]

PLoS Pathogens, 2017
HIV-specific CD8+ T-cell responses limit viral replication in untreated infection. After the initiation of antiretroviral therapy (ART), these responses decay and the infected cell population that remains is commonly considered to be invisible to T-cells.
Allison S Thomas, Kimberley L Jones, Rajesh T Gandhi, Deborah K McMahon, Joshua C Cyktor, Dora Chan, Szu-Han Huang, Ronald Truong, Alberto Bosque, Amanda B Macedo, Colin Kovacs, Erika Benko, Joseph J Eron, Ronald J Bosch, Christina M Lalama, Samuel Simmens, Bruce D Walker, John W Mellors, R Brad Jones   +18 more
doaj   +1 more source

A Yersinia pestis tat mutant is attenuated in bubonic and small-aerosol pneumonic challenge models of infection but not as attenuated by intranasal challenge. [PDF]

PLoS ONE, 2014
Bacterial proteins destined for the Tat pathway are folded before crossing the inner membrane and are typically identified by an N-terminal signal peptide containing a twin arginine motif.
Joel Bozue, Christopher K Cote, Taylor Chance, Jeffrey Kugelman, Steven J Kern, Todd K Kijek, Amy Jenkins, Sherry Mou, Krishna Moody, David Fritz, Camenzind G Robinson, Todd Bell, Patricia Worsham   +12 more
doaj   +1 more source

Signature molecules expressed differentially in a liver disease stage-specific manner by HIV-1 and HCV co-infection. [PDF]

PLoS ONE, 2018
To elucidate HIV-1 co-infection-induced acceleration of HCV liver disease and identify stage-specific molecular signatures, we applied a new high-resolution molecular screen, the Affymetrix GeneChip Human Transcriptome Array (HTA2.0), to HCV-mono- and ...
Amanda Whitmill, Seongcheol Kim, Vivian Rojas, Fahad Gulraiz, Kazi Afreen, Mamta Jain, Meharvan Singh, In-Woo Park   +7 more
doaj   +1 more source

Demonstration that orf2 Encodes the Feline Immunodeficiency Virus Transactivating (Tat) Protein and Characterization of a Unique Gene Product with Partial Rev Activity [PDF]

Journal of Virology, 1999
ABSTRACT The long PCR technique was used to amplify the three size classes of viral mRNAs produced in cells infected by feline immunodeficiency virus (FIV). We identified in the env region a new splice acceptor site that generated two transcripts, each coding for an 11-kDa protein, p11
A, de Parseval, J H, Elder
openaire   +2 more sources

Tn6188 - A Novel Transposon in Listeria monocytogenes Responsible for Tolerance to Benzalkonium Chloride [PDF]

, 2013
peer-reviewedControlling the food-borne pathogen Listeria (L.) monocytogenes is of great importance from a food safety perspective, and thus for human health.
Cotter, Paul D., Guinane, Caitriona M., Muhterem-Uyar, Meryem, Muller, Anneliese, Rychli, Kathrin, Schmitz-Esser, Stephan, Stessl, Beatrix, Wagner, Martin, Zaiser, Andreas   +8 more
core   +6 more sources

STR-based feature extraction and selection for genetic feature discovery in neurological disease genes

Scientific Reports, 2023
Gene expression, often determined by single nucleotide polymorphisms, short repeated sequences known as short tandem repeats (STRs), structural variants, and environmental factors, provides means for an organism to produce gene products necessary to live.
Jasbir Dhaliwal, John Wagner
doaj   +1 more source

Potent Inhibition of Human Immunodeficiency Virus Type 1 (HIV-1) Gene Expression and Virus Production by an HIV-2 Tat Activation-Response RNA Decoy [PDF]

Journal of Virology, 1999
ABSTRACT Tat activation-response region (TAR) decoys have been developed for use in gene therapy for people infected with human immunodeficiency virus type 1 (HIV-1). When a TAR RNA decoy is overexpressed, it will bind Tat, thus leaving less of this crucial protein to bind to and activate the natural transcriptional promoter of HIV-1 ...
C M, Browning, L, Cagnon, P D, Good, J, Rossi, D R, Engelke, D M, Markovitz   +5 more
openaire   +2 more sources