Results 1 to 10 of about 1,028,945 (306)

Expression and diagnostic values of ferroptosis-related genes in coronavirus-associated viral sepsis

Frontiers in Medicine
AimThe aim of this study is to investigate the differential expression and diagnostic value of ferroptosis-related genes in coronavirus-associated viral sepsis.MethodsThis study was conducted in two sequential phases: (1) identification of differentially
Yidan Zhang, Shaoduo Wu, Xiaoyan Li
doaj   +1 more source

Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus

BMC Evolutionary Biology, 2010
Background The influenza A virus is an important infectious cause of morbidity and mortality in humans and was responsible for 3 pandemics in the 20th century. As the replication of the influenza virus is based on its host's machinery, codon usage of its
Wong Emily HM, Smith David K, Rabadan Raul, Peiris Malik, Poon Leo LM   +4 more
doaj   +1 more source

Role of HIV RNA structure in recombination and speciation: romping in purine A, keeps HTLV away

, 2013
Extreme enrichment of the human immunodeficiency virus (HIV-1) RNA genome for the purine A parallels the mild purine-loading of the RNAs of most organisms.
Forsdyke, Donald R.
core   +1 more source

Elongin B-Mediated Epigenetic Alteration of Viral Chromatin Correlates with Efficient Human Cytomegalovirus Gene Expression and Replication

mBio, 2011
Elongins B and C are members of complexes that increase the efficiency of transcriptional elongation by RNA polymerase II (RNAPII) and enhance the monoubiquitination of histone H2B, an epigenetic mark of actively transcribed genes.
Jiwon Hwang, Ryan T. Saffert, Robert F. Kalejta   +2 more
doaj   +1 more source

Insights into the Composition and Function of Virus Communities During Acetic Acid Fermentation of Shanxi Aged Vinegar

Foods
Viruses play a regulatory role in microbial ecology. Traditional fermented foods have complex fermentation environments with abundant viral participation, yet current research on viral communities in fermented foods remains insufficient.
Zhen Yu, Huizi Zhao, Tingting Ma, Xujiao Zhang, Yufeng Yan, Yini Zhu, Yongjian Yu   +6 more
doaj   +1 more source

Counteracting FOX proteins epigenetically control the herpesvirus lytic-latent balance

Nature Communications
The lytic-latent balance is a major viral persistence strategy and obstacle to curing viral diseases, yet its mechanisms remain poorly understood.
Yuhang Xiang, Xiyuan Yang, Juncheng Zhang, Fujun Hou, Yue Deng, Hui Fu, Hyung Suk Oh, Qiongyan Wang, Siyu Chen, Zeyu Sun, Biswajit Das, Yao Yu Yeo, Jean M. Pesola, Pritha Sen, Sizun Jiang, David M. Knipe, Donald M. Coen, Dongli Pan   +17 more
doaj   +1 more source

Importance of Target Gene Locus on the Stability of Recombinant Viruses in the Baculovirus Expression System

Viruses
In the baculovirus expression system, recombinant viruses generated via bacmids often exhibit reduced expression and genetic stability of target genes during serial passages.
Jong Ho Lee, Dong-Hyun Lee, Hyuk-Jin Moon, Soo Dong Woo   +3 more
doaj   +1 more source

Expression of DNA repair and cell cycle control genes in HPV infection

Вавиловский журнал генетики и селекции
One of the main etiological factors in the development of cervical cancer is infection with human papillomavirus (HPV). At the same time, the risk of developing a malignant process increases with an increase in viral load.
E. V. Mashkina, V. V. Volchik, E. S. Muzlaeva, E. G. Derevyanchuk   +3 more
doaj   +1 more source

Nanotechnology-based non-viral vectors for gene delivery in cardiovascular diseases

Frontiers in Bioengineering and Biotechnology
Gene therapy is a technique that rectifies defective or abnormal genes by introducing exogenous genes into target cells to cure the disease. Although gene therapy has gained some accomplishment for the diagnosis and therapy of inherited or acquired ...
Liping Jiao, Zhuokai Sun, Zhihong Sun, Jie Liu, Guanjun Deng, Xiaozhong Wang, Xiaozhong Wang   +6 more
doaj   +1 more source

Cellular antibody affinity-based CRISPR screening identifies JUNB as a broadly acting antiviral factor. [PDF]

Proc Natl Acad Sci U S A
Waild NC, Ciesla JH, Schafer XL, Munger J.   +3 more
europepmc   +1 more source