Results 21 to 30 of about 755,314 (318)
Journal of Orofacial Sciences, 2013 Gene therapy "the use of genes as medicine" involves the transfer of a therapeutic or working copy of a gene into specific cells of an individual in order to repair a faulty gene copy. The technique may be used to replace a faulty gene, or to introduce a
Sudip Indu +3 more
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CRISPR Spacers Indicate Preferential Matching of Specific Virioplankton Genes
mBio, 2019 Viral infection exerts selection pressure on marine microbes, as virus-induced cell lysis causes 20 to 50% of cell mortality, resulting in fluxes of biomass into oceanic dissolved organic matter.
Daniel J. Nasko +5 more
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Divergent Traits and Ligand-Binding Properties of the Cytomegalovirus CD48 Gene Family
Viruses, 2020 The genesis of gene families by the capture of host genes and their subsequent duplication is a crucial process in the evolution of large DNA viruses. CD48 is a cell surface molecule that interacts via its N-terminal immunoglobulin (Ig) domain with the ...
Pablo Martínez-Vicente +3 more
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Interferon-induced genes of the expanded IFIT family show conserved antiviral activities in non-mammalian species. [PDF]
PLoS ONE, 2014 Interferon-induced proteins with tetratricopeptide repeats (IFITs) are involved in the protective response to viral infection, although the precise mechanism of IFITs for reducing viral proliferation is currently unknown.
Mónica Varela +8 more
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Reads Binning Improves the Assembly of Viral Genome Sequences From Metagenomic Samples
Frontiers in Microbiology, 2021 Metagenomes can be considered as mixtures of viral, bacterial, and other eukaryotic DNA sequences. Mining viral sequences from metagenomes could shed insight into virus–host relationships and expand viral databases.
Kai Song
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Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis. [PDF]
, 2012 BACKGROUND: Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus of the Reoviridae family, which encodes its genes in ten linear dsRNA segments.
Roy Polly +8 more
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Identification of the Immediate-Early Genes of Cyprinid Herpesvirus 2
Viruses, 2020 Cyprinid herpesvirus 2 (CyHV-2), which infects goldfish and crucian carp causing high mortality, is an emerging viral pathogen worldwide. The genome of CyHV-2 is large and comprises double-stranded DNA, including several genes similar to cyprinid ...
Ruizhe Tang +4 more
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Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach. [PDF]
PLoS Genetics, 2010 Viruses have exerted a constant and potent selective pressure on human genes throughout evolution. We utilized the marks left by selection on allele frequency to identify viral infection-associated allelic variants.
Matteo Fumagalli +6 more
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BMC Genomics, 2011 Background Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) are related human tumor viruses that cause primary effusion lymphomas (PEL) and Burkitt's lymphomas (BL), respectively.
Dresang Lindsay R +11 more
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Frontiers in Immunology, 2019 The activation of innate immunity by viral nucleic acids present in the cytoplasm plays an essential role in controlling viral infection in both immune and non-immune cells.
Xin Xie +3 more
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