Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. [PDF]
Cellular and viral microRNAs (miRNAs) are involved in many different processes of key importance and more than 10,000 miRNAs have been identified so far.
Seto, Eri +23 more
core +1 more source
Localization of Frog Virus 3 Conserved Viral Proteins 88R, 91R, and 94L
The characterization of the function of conserved viral genes is central to developing a greater understanding of important aspects of viral replication or pathogenesis.
Emily Penny, Craig R. Brunetti
doaj +1 more source
Subversion of host immune surveillance is a crucial step in viral pathogenesis. Epstein-Barr virus (EBV) encodes two immune evasion gene products, BCRF1 (viral IL-10) and BPLF1 (deubiquitinase/deneddylase); both proteins suppress antiviral immune ...
Jessica McKenzie +4 more
doaj +1 more source
The Sorcerer II Global Ocean Sampling Expedition: metagenomic characterization of viruses within aquatic microbial samples. [PDF]
Viruses are the most abundant biological entities on our planet. Interactions between viruses and their hosts impact several important biological processes in the world's oceans such as horizontal gene transfer, microbial diversity and biogeochemical ...
Shannon J Williamson +11 more
doaj +1 more source
The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53 [PDF]
During adenovirus infection, the emphasis of gene expression switches from early genes to late genes in a highly regulated manner. Two gene products, L4-22K and L4-33K, contribute to this switch by activating the Major Late Transcription Unit (MLTU) and ...
Leppard, Keith, Wright, Jordan
core +1 more source
Viral miRNAs confer survival in host cells by targeting apoptosis related host genes
miRNAs are small non-coding RNAs that regulate gene expression by RNA silencing. Like eukaryotic organisms, some viruses also produce miRNAs. While contribution of host miRNA in preventing viral pathogenesis has been studied, how viral miRNA confers ...
Islam, ABMMK, Islam, MS
core +1 more source
Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo [PDF]
There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus origin of replication can be used to activate or increase the expression of ...
Mohr, Hermine +47 more
core +1 more source
Dietary energy drives the dynamic response of bovine rumen viral communities
Background Rumen microbes play a greater role in host energy acquisition than that of gut-associated microbes in monogastric animals. Although genome-enabled advancements are providing access to the vast diversity of uncultivated microbes, our ...
Christopher L. Anderson +2 more
doaj +1 more source
Factors influencing Barley Stripe Mosaic Virus-mediated gene silencing in wheat [PDF]
Virus induced gene silencing (VIGS) is a technology that has been used primarily to target the virus genome in infected plants. However, if the virus genome carries inserts derived from the host plant, the system could be employed to target the mRNAs ...
Cakir, Cahid +3 more
core +1 more source
Assessment of viral community functional potential from viral metagenomes may be hampered by contamination with cellular sequences [PDF]
Although the importance of viruses in natural ecosystems is widely acknowledged, the functional potential of viral communities is yet to be determined. Viral genomes are traditionally believed to carry only those genes that are directly pertinent to the ...
Simon Roux +4 more
doaj +1 more source

