Results 31 to 40 of about 755,314 (318)

Micro RNAs of Epstein-Barr virus promote cell cycle progression and prevent apoptosis of primary human B cells. [PDF]

open access: yes, 2010
Cellular and viral microRNAs (miRNAs) are involved in many different processes of key importance and more than 10,000 miRNAs have been identified so far.
Seto, Eri   +23 more
core   +1 more source

Localization of Frog Virus 3 Conserved Viral Proteins 88R, 91R, and 94L

open access: yesViruses, 2019
The characterization of the function of conserved viral genes is central to developing a greater understanding of important aspects of viral replication or pathogenesis.
Emily Penny, Craig R. Brunetti
doaj   +1 more source

The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex.

open access: yesPLoS Pathogens, 2016
Subversion of host immune surveillance is a crucial step in viral pathogenesis. Epstein-Barr virus (EBV) encodes two immune evasion gene products, BCRF1 (viral IL-10) and BPLF1 (deubiquitinase/deneddylase); both proteins suppress antiviral immune ...
Jessica McKenzie   +4 more
doaj   +1 more source

The Sorcerer II Global Ocean Sampling Expedition: metagenomic characterization of viruses within aquatic microbial samples. [PDF]

open access: yesPLoS ONE, 2008
Viruses are the most abundant biological entities on our planet. Interactions between viruses and their hosts impact several important biological processes in the world's oceans such as horizontal gene transfer, microbial diversity and biogeochemical ...
Shannon J Williamson   +11 more
doaj   +1 more source

The human adenovirus 5 L4 promoter is activated by cellular stress response protein p53 [PDF]

open access: yes, 2013
During adenovirus infection, the emphasis of gene expression switches from early genes to late genes in a highly regulated manner. Two gene products, L4-22K and L4-33K, contribute to this switch by activating the Major Late Transcription Unit (MLTU) and ...
Leppard, Keith, Wright, Jordan
core   +1 more source

Viral miRNAs confer survival in host cells by targeting apoptosis related host genes

open access: yes, 2021
miRNAs are small non-coding RNAs that regulate gene expression by RNA silencing. Like eukaryotic organisms, some viruses also produce miRNAs. While contribution of host miRNA in preventing viral pathogenesis has been studied, how viral miRNA confers ...
Islam, ABMMK, Islam, MS
core   +1 more source

Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo [PDF]

open access: yes, 2011
There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus origin of replication can be used to activate or increase the expression of ...
Mohr, Hermine   +47 more
core   +1 more source

Dietary energy drives the dynamic response of bovine rumen viral communities

open access: yesMicrobiome, 2017
Background Rumen microbes play a greater role in host energy acquisition than that of gut-associated microbes in monogastric animals. Although genome-enabled advancements are providing access to the vast diversity of uncultivated microbes, our ...
Christopher L. Anderson   +2 more
doaj   +1 more source

Factors influencing Barley Stripe Mosaic Virus-mediated gene silencing in wheat [PDF]

open access: yes, 2010
Virus induced gene silencing (VIGS) is a technology that has been used primarily to target the virus genome in infected plants. However, if the virus genome carries inserts derived from the host plant, the system could be employed to target the mRNAs ...
Cakir, Cahid   +3 more
core   +1 more source

Assessment of viral community functional potential from viral metagenomes may be hampered by contamination with cellular sequences [PDF]

open access: yesOpen Biology, 2013
Although the importance of viruses in natural ecosystems is widely acknowledged, the functional potential of viral communities is yet to be determined. Viral genomes are traditionally believed to carry only those genes that are directly pertinent to the ...
Simon Roux   +4 more
doaj   +1 more source

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