Results 51 to 60 of about 1,028,945 (306)
To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. [PDF]
, 2015 Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated to target different stages of the viral life cycle.
Li, Melody MH +2 more
core +1 more source
BMC Biology, 2020 Background Polydnaviruses (PDVs) are mutualistic endogenous viruses inoculated by some lineages of parasitoid wasps into their hosts, where they facilitate successful wasp development.
Fabrice Legeai +16 more
doaj +1 more source
Poliovirus intrahost evolution is required to overcome tissue-specific innate immune responses. [PDF]
, 2017 RNA viruses, such as poliovirus, have a great evolutionary capacity, allowing them to quickly adapt and overcome challenges encountered during infection.
Andino, Raul +6 more
core +3 more sources
Complete genome viral phylogenies suggests the concerted evolution of regulatory cores and accessory satellites. [PDF]
PLoS ONE, 2008 We consider the concerted evolution of viral genomes in four families of DNA viruses. Given the high rate of horizontal gene transfer among viruses and their hosts, it is an open question as to how representative particular genes are of the evolutionary ...
Paolo Marinho de Andrade Zanotto +1 more
doaj +1 more source
Stem-cell-based gene therapy for HIV infection. [PDF]
, 2013 Despite the enormous success of combined anti-retroviral therapy, HIV infection is still a lifelong disease and continues to spread rapidly worldwide. There is a pressing need to develop a treatment that will cure HIV infection.
Kitchen, Scott, Zhen, Anjie
core +2 more sources
PLoS ONE, 2018 Cotesia plutellae (= vestalis) bracovirus (CpBV) is symbiotic to an endoparasitoid wasp, C. plutellae, and plays crucial roles in parasitism against the diamondback moth, Plutella xylostella.
Yonggyun Kim, Sunil Kumar
doaj +1 more source
Materials promoting viral gene delivery
Biomaterials Science, 2020 This review discusses the progress in developing materials that enhance viral transduction, including polymers, peptides, lipids, nanoparticles, and small molecules.
Kübra Kaygisiz +1 more
openaire +4 more sources
Oyster RNA-seq data support the development of Malacoherpesviridae genomics [PDF]
, 2017 The family of double-stranded DNA (dsDNA) Malacoherpesviridae includes viruses able to infect marine mollusks and detrimental for worldwide aquaculture production. Due to fast-occurring mortality and a lack of permissive cell lines, the available data on
Rosani, Umberto, Venier, Paola
core +2 more sources
Coexistence of virome-encoded health-associated genes and pathogenic genes in global habitats
Applied and Environmental MicrobiologyViral remnants constitute approximately 8% of the human genome, reflecting extensive historical gene exchange between viruses and their hosts. Some viral genomes harbor genes acquired through horizontal gene transfer that are associated with potential ...
Min Qian +6 more
doaj +1 more source
Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19
Scientific Reports, 2021 SARS-CoV-2 infection has spread uncontrollably worldwide while it remains unknown how vulnerable populations, such as Down syndrome (DS) individuals are affected by the COVID-19 pandemic.
Ilario De Toma, Mara Dierssen
doaj +1 more source