Results 51 to 60 of about 755,314 (318)

454-Pyrosequencing: A Molecular Battiscope for Freshwater Viral Ecology

open access: yes, 2010
Viruses, the most abundant biological entities on the planet, are capable of infecting organisms from all three branches of life, although the majority infect bacteria where the greatest degree of cellular diversity lies.
Allison, Heather E   +23 more
core   +1 more source

Persistent expression of Cotesia plutellae bracovirus genes in parasitized host, Plutella xylostella.

open access: yesPLoS ONE, 2018
Cotesia plutellae (= vestalis) bracovirus (CpBV) is symbiotic to an endoparasitoid wasp, C. plutellae, and plays crucial roles in parasitism against the diamondback moth, Plutella xylostella.
Yonggyun Kim, Sunil Kumar
doaj   +1 more source

Coexistence of virome-encoded health-associated genes and pathogenic genes in global habitats

open access: yesApplied and Environmental Microbiology
Viral remnants constitute approximately 8% of the human genome, reflecting extensive historical gene exchange between viruses and their hosts. Some viral genomes harbor genes acquired through horizontal gene transfer that are associated with potential ...
Min Qian   +6 more
doaj   +1 more source

Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19

open access: yesScientific Reports, 2021
SARS-CoV-2 infection has spread uncontrollably worldwide while it remains unknown how vulnerable populations, such as Down syndrome (DS) individuals are affected by the COVID-19 pandemic.
Ilario De Toma, Mara Dierssen
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Herpes simplex virus triggers and then disarms a host antiviral response

open access: yes, 2001
Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human ...
Smiley, J R   +5 more
core   +1 more source

Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity

open access: yesmBio, 2018
Defining the specific factors that govern the evolution and transmission of influenza A virus (IAV) populations is of critical importance for designing more-effective prediction and control strategies. Superinfection, the sequential infection of a single
Jiayi Sun, Christopher B. Brooke
doaj   +1 more source

Identification of Viral Taxon-Specific Genes (VTSG): Application to [PDF]

open access: yesGenomics & Informatics, 2018
Virus taxonomy was initially determined by clinical experiments based on phenotype. However, with the development of sequence analysis methods, genotype-based classification was also applied.
Shinduck Kang, Young-Chang Kim
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

T4 genes in the marine ecosystem: studies of the T4-like cyanophages and their role in marine ecology [PDF]

open access: yes, 2010
From genomic sequencing it has become apparent that the marine cyanomyoviruses capable of infecting strains of unicellular cyanobacteria assigned to the genera Synechococcus and Prochlorococcus are not only morphologically similar to T4, but are also ...
N. H. Mann (7607588)   +11 more
core   +1 more source

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