Results 121 to 130 of about 131,368 (156)

Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III. [PDF]

open access: yesNature
McClune CJ   +6 more
europepmc   +1 more source

Human cell lines stably expressing HIV env and tat gene products

Biochemical and Biophysical Research Communications, 1989
A DNA fragment containing the tat, rev and env genes of the human immunodeficiency virus type 1 was inserted into the retroviral vector pZIPneoAU3. The resulting plasmid penvAU3 was transfected into HeLa and psi CRIP cells. Resulting recombinant retroviruses were used to infect HeLa and Jurkat cells. Immunoprecipitation analysis of stable transformants
M A, Sosa   +3 more
openaire   +2 more sources

Transcriptional but not translational regulation of HIV-1 by the tat gene product

Nature, 1988
Human immunodeficiency virus-1 (HIV-1), which causes AIDS (acquired immune deficiency syndrome), possesses an essential gene, tat, whose product, acting through the long terminal repeat (LTR) sequences of HIV-1, activates viral genes and replication. The mechanism by which tat trans-activates HIV genes is unclear.
A P, Rice, M B, Mathews
openaire   +2 more sources

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

Nature, 1987
Human immunodeficiency virus-1 (HIV-1) gene expression is controlled by cellular transcription factors and by virally encoded trans-activation proteins of the HIV-1 tat and art/trs genes, which are essential for viral replication. Tat trans-activates HIV-1 gene expression by interacting with the trans-acting response element (TAR) located within the ...
S Y, Kao   +3 more
openaire   +2 more sources

Modulation of accessory cell function and interleukin-6 production by the HIV-1 tat gene.

American Journal of Respiratory Cell and Molecular Biology, 1994
Manifestations of HIV-1 infection such as fever, hypergammaglobulinemia, and interstitial pneumonitis may be due to increased production of inflammatory cytokines such as interleukin-1 and interleukin-6 (IL-6). Monocytes/macrophages of HIV-1-infected individuals have been noted to produce increased amounts of IL-6, as well as to have enhanced accessory
G K, Iwamoto, S A, Konicek, H L, Twigg
openaire   +2 more sources

Control of the Interferon-Induced 68-Kilodalton Protein Kinase by the HIV-1 tat Gene Product

Science, 1990
The tat -responsive region (TAR) of the human immunodeficiency virus-1 (HIV-1) exhibits a trans-inhibitory effect on translation in vitro by activating the interferon-induced 68-kilodalton protein kinase (p68 kinase).
S, Roy   +5 more
openaire   +2 more sources

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