Results 91 to 100 of about 1,691,605 (342)

Eukaryotic gene regulation [PDF]

Chemistry & Biology, 2000
Basal Transcription Factor Informationhttp://tfiib.med.harvard.edu/transcription/basaltx.htmlEukaryotic Promoter Databasehttp://www.epd.isb-sib.ch/Transcriptional Regulatory Regions Databasehttp://www.bionet.nsc.ru/trrd/TRANSFAChttp://transfac.gbf.de/Homeodomain Resourcehttp://genome.nhgri.nih.gov/homeodomain/The Nuclear Receptor Resourcehttp://nrr ...
openaire   +2 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

ARID1A promotes genomic stability through protecting telomere cohesion

Nature Communications, 2019
Cells with ARID1A mutations exhibit mitotic defects, yet show surprisingly low levels of copy number defects. Here, Zhao et al. resolve this issue by showing that ARID1A loss causes defects in telomere cohesion, which selects against gross alterations in
Bo Zhao, Jianhuang Lin, Lijie Rong, Shuai Wu, Zhong Deng, Nail Fatkhutdinov, Joseph Zundell, Takeshi Fukumoto, Qin Liu, Andrew Kossenkov, Stephanie Jean, Mark G. Cadungog, Mark E. Borowsky, Ronny Drapkin, Paul M. Lieberman, Cory T. Abate-Shen, Rugang Zhang   +16 more
doaj   +1 more source

Animal Models of Chronic Hepatitis Delta Virus Infection Host–Virus Immunologic Interactions

Pathogens, 2015
Hepatitis delta virus (HDV) is a defective RNA virus that has an absolute requirement for a virus belonging to the hepadnaviridae family like hepatitis B virus (HBV) for its replication and formation of new virions.
Rafael Aldabe, Lester Suárez-Amarán, Carla Usai, Gloria González-Aseguinolaza   +3 more
doaj   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

Molecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Elin Borgen, Cecilie Bendigtsen Schirmer, Bjørnar Gilje, Øystein Garred, Jon Lømo, Marius Stensland, Oddmund Nordgård, Ragnhild Sørum Falk, Randi R. Mathiesen, Hege G. Russnes, Jon Amund Kyte, Bjørn Naume   +13 more
wiley   +1 more source

A Sendai virus-based expression system directs efficient induction of chondrocytes by transcription factor-mediated reprogramming

Scientific Reports
Cartilage rarely heals spontaneously once damaged. Osteoarthritis (OA) is the most common degenerative joint disease among the elderly; however, effective treatment for OA is currently lacking.
Jingwen Zhou, Yuya Sekiguchi, Masayuki Sano, Ken Nishimura, Koji Hisatake, Aya Fukuda   +5 more
doaj   +1 more source

RNA-containing extracellular vesicles in infection

RNA Biology
Extracellular vesicles (EVs) are membrane-bound particles released by cells that play vital roles in intercellular communication by transporting diverse biologically active molecules, including RNA molecules, including mRNA, miRNA, lncRNA, and other ...
Kayo Schemiko Almeida, Suélen Andreia Rossi, Lysangela Ronalte Alves   +2 more
doaj   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

REGULATION OF GENES CONTROLLING SYNTHESIS OF THE GALACTOSE PATHWAY ENZYMES IN YEAST [PDF]

, 1966
H. C. Douglas, D C Hawthorne
openalex   +1 more source