Results 91 to 100 of about 2,989,814 (357)
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Associative memory in gene regulation networks
The pattern of gene expression in the phenotype of an organism is determined in part by the dynamical attractors of the organism’s gene regulation network.
Buckley, C. L.+3 more
core
miRNAs as Regulators of Antidiabetic Effects of Fucoidans [PDF]
open access articleDiabetes mellitus is a metabolic disease with a high mortality rate worldwide. MicroRNAs (miRNAs), and other small noncoding RNAs, serve as endogenous gene regulators through binding to specific sequences in RNA and modifying gene ...
Arroo, R. R. J.+8 more
core +1 more source
Eukaryotic gene regulation [PDF]
Basal Transcription Factor Informationhttp://tfiib.med.harvard.edu/transcription/basaltx.htmlEukaryotic Promoter Databasehttp://www.epd.isb-sib.ch/Transcriptional Regulatory Regions Databasehttp://www.bionet.nsc.ru/trrd/TRANSFAChttp://transfac.gbf.de/Homeodomain Resourcehttp://genome.nhgri.nih.gov/homeodomain/The Nuclear Receptor Resourcehttp://nrr ...
openaire +2 more sources
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
Frequency-modulated nuclear localization bursts coordinate gene regulation [PDF]
In yeast, the transcription factor Crz1 is dephosphorylated and translocates into the nucleus in response to extracellular calcium. Here we show, using time-lapse microscopy, that Crz1 exhibits short bursts of nuclear localization (typically lasting 2 ...
Cai, Long+2 more
core +2 more sources
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche+2 more
wiley +1 more source
RNA-containing extracellular vesicles in infection
Extracellular vesicles (EVs) are membrane-bound particles released by cells that play vital roles in intercellular communication by transporting diverse biologically active molecules, including RNA molecules, including mRNA, miRNA, lncRNA, and other ...
Kayo Schemiko Almeida+2 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Hydrogen magnetic reaction gene regulation
A new gene regulation system using weak magnetic field can induce the hydrogen magnetic reaction (HMR) in hydrogen atoms, and subsequently affect the electrostatic polarity of hydrogen bonds in DNA base pairs.
Kim, Yeon Sook+2 more
core