Results 151 to 160 of about 3,082,129 (201)
The RNA revolution in medicine: from gene regulation to clinical therapeutics. [PDF]
Anim Cells Syst (Seoul)Jeong J, Jeong S.
europepmc +1 more source
Distinct effects of tea types and components on circadian rhythm entrainment and clock gene regulation. [PDF]
NPJ Sci FoodZhang J +9 more
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MLL2 facilitates long-range gene regulation through LINE1 elements
Zorro Shahidian L +3 more
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2013
This review concisely highlights the complexity of regulatory events. It provides examples of how interconnectivity of regulatory hubs could maintain transcriptional synergy and orchestrate the proper spatial and temporal patterns of gene expression.
P.W.L. Tai +5 more
+6 more sources
This review concisely highlights the complexity of regulatory events. It provides examples of how interconnectivity of regulatory hubs could maintain transcriptional synergy and orchestrate the proper spatial and temporal patterns of gene expression.
P.W.L. Tai +5 more
+6 more sources
Annual Review of Physiology, 1990
Since the cloning of the somatostatin cDNA and gene, the efforts of a number of laboratories have contributed to the understanding of somatostatin gene expression and regulation. A genetic element located approximately 40 nucleotides upstream from the somatostatin mRNA cap site is important in the expression and cAMP-induced transcription of this ...
O M, Andrisani, J E, Dixon
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Since the cloning of the somatostatin cDNA and gene, the efforts of a number of laboratories have contributed to the understanding of somatostatin gene expression and regulation. A genetic element located approximately 40 nucleotides upstream from the somatostatin mRNA cap site is important in the expression and cAMP-induced transcription of this ...
O M, Andrisani, J E, Dixon
openaire +2 more sources
Thrombosis and Haemostasis, 2012
SummaryThe Aα, Bβ and γ polypeptide chains of fibrinogen are encoded by a three gene cluster on human chromosome four. The fibrinogen genes (FGB-FGA-FGG) are expressed almost exclusively in hepatocytes where their output is coordinated to ensure a sufficient mRNA pool for each chain and maintain an abundant plasma fibrinogen protein level.
Fish, Richard, Neerman Arbez, Marguerite
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SummaryThe Aα, Bβ and γ polypeptide chains of fibrinogen are encoded by a three gene cluster on human chromosome four. The fibrinogen genes (FGB-FGA-FGG) are expressed almost exclusively in hepatocytes where their output is coordinated to ensure a sufficient mRNA pool for each chain and maintain an abundant plasma fibrinogen protein level.
Fish, Richard, Neerman Arbez, Marguerite
openaire +2 more sources
Regulation of Angiotensinogen Gene
American Journal of Hypertension, 1989The development of recombinant DNA technology has introduced new directions for the study of the angiotensinogen molecule. The cloning and sequencing of the human and rat cDNAs demonstrate the similarity of angiotensinogen to various serine protease inhibitors produced by the liver and was the beginning of studies looking for new physiological roles of
Clauser, E. +3 more
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2016
Gene therapy represents a promising approach for the treatment of monogenic and multifactorial neurological disorders. It can be used to replace a missing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells ...
Ludivine, Breger +3 more
openaire +2 more sources
Gene therapy represents a promising approach for the treatment of monogenic and multifactorial neurological disorders. It can be used to replace a missing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells ...
Ludivine, Breger +3 more
openaire +2 more sources