Results 191 to 200 of about 2,989,814 (357)

Comparative analysis of gene regulation in single cells using Compass. [PDF]

Cell Rep Methods
Wan C, Qu Y, Ye Z, Zhang T, Ma H, Chen M, Hou W, Ji Z.   +7 more
europepmc   +1 more source

Threonine deaminase from Escherichia coli. II. Maturation and physical properties of the enzyme from a mutant altered in its regulation of gene expression.

, 1975
David H. Calhoun, J Kuska, G. Wesley Hatfield   +2 more
openalex   +1 more source

Functional analysis of DNA sequences responsible for ethylene regulation of a bean chitinase gene in transgenic tobacco. [PDF]

, 1989
Karen Broglie, Phyllis Biddle, Ross Cressman, Richard Broglie   +3 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Gene regulation by convergent promoters. [PDF]

Nat Genet
Wiechens E, Vigliotti F, Siniuk K, Schwarz R, Schwab K, Riege K, van Bömmel A, Görlich I, Bens M, Sahm A, Groth M, Sammons MA, Loewer A, Hoffmann S, Fischer M.   +14 more
europepmc   +1 more source

Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide. [PDF]

, 1987
Robert C. Fuhlbrigge, David Chaplin, Jeanne-Marie Kíely, Emil R. Unanue   +3 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Engineering novel CRISPRi repressors for highly efficient mammalian gene regulation. [PDF]

Genome Biol
Kristof A, Karunakaran K, Allen C, Mizote P, Briggs S, Jian Z, Nash P, Blazeck J.   +7 more
europepmc   +1 more source

Nitrogen control in Salmonella : Regulation by the glnR and glnF gene products

, 1979
Sydney Kustu, Doris Burton, Emilio García García, Linda L. McCarter, Nancy McFarland   +4 more
openalex   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source