Results 191 to 200 of about 1,691,605 (342)

Regulation of expression of Adh genes in maize.

, 1976
Drew Schwartz
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Gene regulation and signaling pathways in immune response to respiratory sensitizers: a database analysis. [PDF]

Front Immunol
Jefferis T, Liu JY, Griffin KL, Gibb M, Sayes CM.   +4 more
europepmc   +1 more source

Genes control of rates development as components of regulation stability of Triticum aestivum L. to biotic stress under conditions in vitro

, 1970
O. O. Avksentiieva, N. V. Terentiieva
openalex   +2 more sources

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

AnomalGRN: deciphering single-cell gene regulation network with graph anomaly detection. [PDF]

BMC Biol
Zhou Z, Wei J, Liu M, Zhuo L, Fu X, Zou Q.   +5 more
europepmc   +1 more source

Ir Gene Regulation at the Single Cell Level

, 1978
Susan K. Pierce, Norman R. Klinman
openalex   +1 more source

Evidence that the familial adenomatous polyposis gene is involved in a subset of colon cancers with a complementable defect in c-myc regulation. [PDF]

, 1989
M D Erisman, J. K. Scott, Susan M. Astrin   +2 more
openalex   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Flexibility and sensitivity in gene regulation out of equilibrium. [PDF]

Proc Natl Acad Sci U S A
Mahdavi SD, Salmon GL, Daghlian P, Garcia HG, Phillips R.   +4 more
europepmc   +1 more source