Results 211 to 220 of about 12,124,124 (398)

RicemicroRNA171f/SCL6module enhances drought tolerance by regulation of flavonoid biosynthesis genes

, 2022
Taeyoung Um, JooHee Choi, Tae-Hyeon Park, Pil Joong Chung, Se Eun Jung, Jae Sung Shim, Youn Shic Kim, Ik‐Young Choi, Soo Chul Park, Se‐Jun Oh, Jun Sung Seo, Ju‐Kon Kim   +11 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A CRISPRi Gene Regulation System for Bifidobacteria. [PDF]

Microb Biotechnol
Friess L, van Sinderen D, Lee C.
europepmc   +1 more source

Regulation of gene transcription by estrogen and progesterone. Lack of hormonal effects on transcription by Escherichia coli RNA polymerase.

, 1980
R D Palmiter, D.C. Lee
openalex   +1 more source

Regulation of chromatin accessibility and gene expression in the developing hippocampal primordium by LIM-HD transcription factor LHX2

, 2023
Varun Suresh, Bhavana Muralidharan, Saurabh J. Pradhan, Mahima Bose, Leora D’Souza, Arpan Parichha, Puli Chandramouli Reddy, Sanjeev Galande, Shubha Tole   +8 more
openalex   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Advances in miRNA research: Unraveling the complexities of gene regulation. [PDF]

Animal Model Exp Med
Zheng J, Zhang G, Ren L.
europepmc   +1 more source

Low Oxygen Stress During Early Development Influences Regulation of Hypoxia-Response Genes in Farmed Atlantic Salmon (Salmo salar) [PDF]

, 2020
Tara Kelly, Hanne Johnsen, Erik Burgerhout, Helge Tveiten, Tina Thesslund, Øivind Andersen, Nicholas A. Robinson   +6 more
openalex   +1 more source

Transcriptional regulation of the tyrosine aminotransferase gene [PDF]

, 1989
Boshart, Michael, Dumont, J. E., Nitsch, Doris, Nunez, J., Schmidt, Andrea, Schütz, Günther, Weih, Falk   +6 more
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source