Results 241 to 250 of about 3,132,999 (350)

MeCP2 at the crossroads of hypoxia, oxidative stress, and gene regulation in Rett syndrome. [PDF]

Epigenomics
Huang JL, Sharifi O, Yasui DH, LaSalle JM.   +3 more
europepmc   +1 more source

CpG island evolution in the mammalian DHRS4 gene cluster and its role in the regulation of gene transcription

, 2016
Zhuanzhuan Su, G. Liu, Xiao Song, Bin Liang, Xiao Chang, Dongyang Huang   +5 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Polygenic prediction and gene regulation networks. [PDF]

R Soc Open Sci
Poyatos JF.
europepmc   +1 more source

Genes and gene regulation

The Journal of Physical Fitness and Sports Medicine, 2018
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Revisiting models of enhancer-promoter communication in gene regulation. [PDF]

Genome Res
Barshad G, Danko CG.
europepmc   +1 more source

Genes and gene regulation

The Journal of Physical Fitness and Sports Medicine, 2017
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Distinct effects of tea types and components on circadian rhythm entrainment and clock gene regulation. [PDF]

NPJ Sci Food
Zhang J, Li H, Ma C, Zhang S, Wu G, Shen B, Chen B, Chen L, Zhang Q, Yang G.   +9 more
europepmc   +1 more source