Results 281 to 290 of about 3,161,105 (354)

Integrative transcriptomic and machine learning approaches to decipher mitochondrial gene regulation in severe Plasmodium vivax malaria. [PDF]

Malar J
Roy P, Aggarwal Y, Kochar SK, Kochar DK, Das A.   +4 more
europepmc   +1 more source

Cloning, regulation, and promoter analysis of the cadA gene in Dictyostelium discoideum

, 1999
Chunzhong Yang
openalex   +1 more source

Identification of the phosphatidylethanolamine-binding protein gene family in wintersweet (Chimonanthus praecox) and regulation of flowering by CpTFL1s

Huafeng Wu, Bin Liu, Yinzhu Cao, Guanpeng Ma, Xiaowen Zheng, Haoxiang Zhu, Xingrong Song, Shunzhao Sui   +7 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Interplay Between 3D Chromatin Architecture and Gene Regulation at the <i>APOE</i> Locus Contributes to Alzheimer's Disease Risk. [PDF]

Int J Mol Sci
Lee EG, Leong L, Chen S, Tulloch J, Yu CE.   +4 more
europepmc   +1 more source

Molecular mechanisms underlying the regulation of tumour suppressor genes in lung cancer

Lee Jy, Richie R. Bhandare, Sai H. S. Boddu, Afzal B. Shaik, Lakshmana Prabu Saktivel, Gaurav Gupta, Poonam Negi, Muna Barakat, Sachin Kumar Singh, Kamal Dua, Dinesh Kumar Chellappan   +10 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Sex-dimorphic gene regulation in murine macrophages across niches. [PDF]

Immunol Cell Biol
McGill CJ, White OS, Lu RJ, Sampathkumar NK, Benayoun BA.   +4 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

rBCG-LTAK63 enhances protection against tuberculosis by inducing autophagy and circadian gene regulation. [PDF]

Front Immunol
Marques-Neto LM, Trentini MM, Moreno ACR, Eto SF, Carvalho ACO, Neto APS, Amaral MS, Martins AGC, Gonçalves ANA, Chudzinski-Tavassi AM, Kanno AI, Tagliabue A, Boraschi D, Verjovski-Almeida S, Nakaya H, Farias LP, Ramos PIP, Leite LCC.   +17 more
europepmc   +1 more source