Results 311 to 320 of about 2,989,814 (357)
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Cellular and Molecular Life Sciences (CMLS), 1999
A recent explosion in the identification of new clock components in cyanobacteria, fungi, insects, mammals as well as potential candidates in plants has uncovered common themes among the structure, function and regulation of these components. Positive and negative interactions that are organized in negative feedback loops have been found crucial for ...
Christian Heintzen +3 more
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A recent explosion in the identification of new clock components in cyanobacteria, fungi, insects, mammals as well as potential candidates in plants has uncovered common themes among the structure, function and regulation of these components. Positive and negative interactions that are organized in negative feedback loops have been found crucial for ...
Christian Heintzen +3 more
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Annual Review of Physiology, 1990
Since the cloning of the somatostatin cDNA and gene, the efforts of a number of laboratories have contributed to the understanding of somatostatin gene expression and regulation. A genetic element located approximately 40 nucleotides upstream from the somatostatin mRNA cap site is important in the expression and cAMP-induced transcription of this ...
Jack E. Dixon, Ourania M. Andrisani
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Since the cloning of the somatostatin cDNA and gene, the efforts of a number of laboratories have contributed to the understanding of somatostatin gene expression and regulation. A genetic element located approximately 40 nucleotides upstream from the somatostatin mRNA cap site is important in the expression and cAMP-induced transcription of this ...
Jack E. Dixon, Ourania M. Andrisani
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2013
This review concisely highlights the complexity of regulatory events. It provides examples of how interconnectivity of regulatory hubs could maintain transcriptional synergy and orchestrate the proper spatial and temporal patterns of gene expression.
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This review concisely highlights the complexity of regulatory events. It provides examples of how interconnectivity of regulatory hubs could maintain transcriptional synergy and orchestrate the proper spatial and temporal patterns of gene expression.
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Gene Regulation By Tetracyclines
2004Gene regulation by tetracyclines has become a widely-used tool to study gene functions in pro- and eukaryotes. This regulatory system originates from Gram-negative bacteria, in which it fine-tunes expression of a tetracycline-specific export protein mediating resistance against this antibiotic.
Wolfgang Hillen, Christian Berens
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Current Opinion in Genetics & Development, 2006
The role of small RNAs as key regulators of mRNA turnover and translation has been well established. Recent advances indicate that the small RNAs termed microRNAs play important roles in animal development and physiology. Cellular activities such as proliferation, morphogenesis, apoptosis and differentiation are regulated by microRNAs.
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The role of small RNAs as key regulators of mRNA turnover and translation has been well established. Recent advances indicate that the small RNAs termed microRNAs play important roles in animal development and physiology. Cellular activities such as proliferation, morphogenesis, apoptosis and differentiation are regulated by microRNAs.
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Gene regulation by riboswitches
Nature Reviews Molecular Cell Biology, 2004Riboswitches are complex folded RNA domains that serve as receptors for specific metabolites. These domains are found in the non-coding portions of various mRNAs, where they control gene expression by harnessing allosteric structural changes that are brought about by metabolite binding.
Maumita Mandal, Ronald R. Breaker
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British Medical Bulletin, 1991
A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
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A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
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Gene regulation by phytochrome
Trends in Genetics, 1988Abstract Many responses of plants to phytochrome involve alterations in gene expression. Recent studies with transgenic plants as an expression system have led to the identification of cis -acting elements that mediate responses to phytochrome and light.
Ferenc Nagy, Nam-Hai Chua, Steve A. Kay
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2016
Gene therapy represents a promising approach for the treatment of monogenic and multifactorial neurological disorders. It can be used to replace a missing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells ...
Ludivine S. Breger +3 more
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Gene therapy represents a promising approach for the treatment of monogenic and multifactorial neurological disorders. It can be used to replace a missing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells ...
Ludivine S. Breger +3 more
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Gene regulation of steroidogenesis
The Journal of Steroid Biochemistry and Molecular Biology, 1995The biosynthesis of various steroid hormones in animal tissues are catalyzed by six forms of cytochrome P450 and two hydroxysteroid dehydrogenases. The tissue-specific expression of these enzymes, which are under the control of the pituitary gland and mainly regulated at the transcriptional level, determines the steroidogenesis of animal tissues ...
Ken Ichirou Morohashi, Tsuneo Omura
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