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GroupAdaBoost for Selecting Important Genes
Fifth IEEE Symposium on Bioinformatics and Bioengineering (BIBE'05), 2006This paper proposes GroupAdaBoost as a variant of AdaBoost for statistical pattern recognition. The objective of the proposed algorithm is to solve the p /spl Gt/ n problem arisen in bioinformatics. Typically, p is the number of investigated genes and n is number of individuals in a microarray experiment for observing gene expressions in a problem to ...
Takashi Takenouchi +2 more
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On Stability of Ensemble Gene Selection
2015When the feature selection process aims at discovering useful knowledge from data, not just producing an accurate classifier, the degree of stability of selected features is a very crucial issue. In the last years, the ensemble paradigm has been proposed as a primary avenue for enhancing the stability of feature selection, especially in high ...
DESSI, NICOLETTA +2 more
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On the Complexity of Gene Marker Selection
2010 Eleventh Brazilian Symposium on Neural Networks, 2010Gene marker selection from gene expression profiles has been extensively investigated in the Bioinformatics literature. The aim is usually to find a compact set of genes potentially correlated to a particular disease, which can then be candidate targets for new drugs and treatments. Available gene expression data sets are often noisy and sparse, having
Ana Carolina Lorena +3 more
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Gene selection for breast cancer
2012 20th Signal Processing and Communications Applications Conference (SIU), 2012Breast cancer can be fatal and so it is very dangerous. Early diagnosis of breast cancer has been playing very important role on treatment of the disease. Recently, gene technology has been widely used in cancer diagnosis. A microarray is a tool for analyzing gene expression.
Oktay Yildiz +4 more
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Natural selection on gene expression
Trends in Genetics, 2006Changes in genetic regulation contribute to adaptations in natural populations and influence susceptibility to human diseases. Despite their potential phenotypic importance, the selective pressures acting on regulatory processes in general and gene expression levels in particular are largely unknown.
Yoav, Gilad +2 more
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Gene selection for Brain Cancer Classification
2006 International Conference of the IEEE Engineering in Medicine and Biology Society, 2006With the introduction of microarray, cancer classification, diagnosis and prediction are made more accurate and effective. However, the final outcome of the data analyses very much depend on the huge number of genes with relatively small number of samples present in each experiment.
Yuk Yee Leung +3 more
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Aesthetic selection of naked genes
Proceedings of the 15th ACM international conference on Multimedia, 2007The problem of genetic representation in (creative) evolutionary systems that aspire to taking part in cultural production is reformulated in the more general terms of the necessary structuring of the search space. Cumulative (aesthetic) selection of "naked genes" is discussed as an alternative approach whereby no germ-line/somatic-line distinction is ...
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Natural Selection and the Complexity of the Gene
Nature, 1969Conflict between the idea of natural selection and the idea of the uniqueness of the gene does not seem too near to a solution yet.
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Selection of Candidate Genes in Hypertension
2005Essential hypertension is a common disease with multifactorial etiology affecting up to 10 million individuals in the United Kingdom alone. Current knowledge of the genetic contribution to this trait is restricted to a number of rare variants that produce hypertensive phenotypes in a Mendelian fashion and to genes highlighted by work on blood pressure ...
Charles A, Mein +2 more
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Selective gene mutation in MEL cells
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1992MEL cells, undergoing erythroid differentiation and parasynchronized by dimethyl sulfoxide (DMSO) induction, were irradiated with a 3-s pulse of UV light at sublethal dose. A large number of clones deficient in different gene functions are found in the progeny of the treated cells, if the pulse irradiation is performed 18-24 h from the start of DMSO ...
FORESTI, MAGDA +2 more
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