Results 21 to 30 of about 1,213,334 (312)

The Unsupervised Feature Selection Algorithms Based on Standard Deviation and Cosine Similarity for Genomic Data Analysis

open access: yesFrontiers in Genetics, 2021
To tackle the challenges in genomic data analysis caused by their tens of thousands of dimensions while having a small number of examples and unbalanced examples between classes, the technique of unsupervised feature selection based on standard deviation
Juanying Xie   +5 more
doaj   +1 more source

Comparison of Methods for Feature Selection in Clustering of High-Dimensional RNA-Sequencing Data to Identify Cancer Subtypes

open access: yesFrontiers in Genetics, 2021
Cancer subtype identification is important to facilitate cancer diagnosis and select effective treatments. Clustering of cancer patients based on high-dimensional RNA-sequencing data can be used to detect novel subtypes, but only a subset of the features
David Källberg   +4 more
doaj   +1 more source

Gene selection in cox regression model based on a new adaptive elastic net penalty [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2020
Regression analysis is great of interest in several studies, especially in medicine. The Cox regression model is one of the most important models of regression used in the medical field.
Oday Alskal, Zakariya Algamal
doaj   +1 more source

A two-stage hybrid gene selection algorithm combined with machine learning models to predict the rupture status in intracranial aneurysms

open access: yesFrontiers in Neuroscience, 2022
An IA is an abnormal swelling of cerebral vessels, and a subset of these IAs can rupture causing aneurysmal subarachnoid hemorrhage (aSAH), often resulting in death or severe disability.
Qingqing Li   +9 more
doaj   +1 more source

A Probabilistic Multi-Objective Artificial Bee Colony Algorithm for Gene Selection [PDF]

open access: yesJournal of Universal Computer Science, 2019
Microarray technology is widely used to report gene expression data. The inclusion of many features and few samples is one of the characteristic features of this platform. In order to define significant genes for a particular disease, the problem of high-
Zeynep Ozger, Bulent Bolat, Banu Diri
doaj   +3 more sources

Determination of the Selection Capacity of Antibiotics for Gene Selection [PDF]

open access: yesBiotechnology Journal, 2018
Choosing a potent selection antibiotic (SA), is a crucial success factor when creating stably transfected cell lines using an antibiotic selection marker. The selection capacity of this antibiotic is defined as its ability to kill sensitive, untransfected parental cells, while leaving resistant, transfected cells unharmed.
Iris, Delrue   +4 more
openaire   +2 more sources

Gene-specific expression noise evolves in a model with selection. [PDF]

open access: yes, 2023
A—The distribution of expression levels of an example gene throughout evolution in populations evolved under stabilizing selection on gene expression level and under neutrality.
Tanvi Madaan (15332567)   +2 more
core   +1 more source

Gene selection: a Bayesian variable selection approach [PDF]

open access: yesBioinformatics, 2003
Abstract Selection of significant genes via expression patterns is an important problem in microarray experiments. Owing to small sample size and the large number of variables (genes), the selection process can be unstable. This paper proposes a hierarchical Bayesian model for gene (variable) selection.
Kyeong Eun Lee   +4 more
openaire   +2 more sources

A Machine Learning Method to Trace Cancer Primary Lesion Using Microarray-Based Gene Expression Data

open access: yesFrontiers in Oncology, 2022
Cancer of unknown primary site (CUP) is a heterogeneous group of cancers whose tissue of origin remains unknown after detailed investigation by conventional clinical methods. The number of CUP accounts for roughly 3%–5% of all human malignancies.
Qingfeng Lu   +6 more
doaj   +1 more source

Translational selection on SHH genes [PDF]

open access: yesGenetics and Molecular Biology, 2010
Codon usage bias has been observed in various organisms. In this study, the correlation between SHH genes expression in some tissues and codon usage features was analyzed by bioinformatics. We found that translational selection may act on compositional features of this set of genes.
Hajjari, Mohammadreza   +2 more
openaire   +5 more sources

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