Results 31 to 40 of about 1,119,682 (262)

Species versus gene selection [PDF]

open access: yesGenetics Selection Evolution, 1989
Author(s): Tsakas, S. C. | Abstract: Species selection has been recently promoted (Gould a Eldredge, 1988a, 1988b) as the driving force in macroevolution, and viewed as an explanation for the variability in rates observed, both temporally and spatially, at the phenotypic level. This has rekindled the contention between microevolutionists (Maynard Smith,
openaire   +5 more sources

Using Supervised Learning Methods for Gene Selection in RNA-Seq Case-Control Studies

open access: yesFrontiers in Genetics, 2018
Whole transcriptome studies typically yield large amounts of data, with expression values for all genes or transcripts of the genome. The search for genes of interest in a particular study setting can thus be a daunting task, usually relying on automated
Stephane Wenric   +2 more
doaj   +1 more source

A Gene Selection Approach based on Clustering for Classification Tasks in Colon Cancer

open access: yesAdvances in Distributed Computing and Artificial Intelligence Journal, 2016
Gene selection (GS) is an important research area in the analysis of DNA-microarray data, since it involves gene discovery meaningful for a particular target annotation or able to discriminate expression profiles of samples coming from different ...
José Antonio CASTELLANOS GARZÓN   +1 more
doaj   +1 more source

Genes, individuals, and kin selection [PDF]

open access: yesProceedings of the National Academy of Sciences, 1981
The altruistic-gene theory of kin selection requires conditions so improbable that its reality is doubtful. The gene-quantity theory, including the theory of inclusive fitness, assumes that selection acts on sums of kins' genes, but no effective mechanism is apparent.
openaire   +2 more sources

IMPROVED GENE SELECTION FOR CLASSIFICATION OF MICROARRAYS [PDF]

open access: yesBiocomputing 2003, 2002
In this paper we derive a method for evaluating and improving techniques for selecting informative genes from microarray data. Genes of interest are typically selected by ranking genes according to a test-statistic and then choosing the top k genes. A problem with this approach is that many of these genes are highly correlated.
Jäger, J., Sengupta, R., Ruzzo, W.
openaire   +4 more sources

Biomarker Gene Signature Discovery Integrating Network Knowledge

open access: yesBiology, 2012
Discovery of prognostic and diagnostic biomarker gene signatures for diseases, such as cancer, is seen as a major step towards a better personalized medicine.
Holger Fröhlich, Yupeng Cun
doaj   +1 more source

A Gene Selection Method for Cancer Classification [PDF]

open access: yesComputational and Mathematical Methods in Medicine, 2012
This paper proposes a method to select a set of genes from a large number of genes with the ability of classifying types of diseases. The proposed gene selection method is designed according to correlation analysis and the concept of 95% reference range. The method is very simple and uses the information of all genes.
Xiaodong Wang 0003, Jun Tian
openaire   +2 more sources

Hybrid Symmetrical Uncertainty and Reference Set Harmony Search Algorithm for Gene Selection Problem

open access: yesMathematics, 2022
Selecting the most miniature possible set of genes from microarray datasets for clinical diagnosis and prediction is one of the most challenging machine learning tasks. A robust gene selection technique is required to identify the most significant subset
Salam Salameh Shreem   +3 more
doaj   +1 more source

New Bio-Marker Gene Discovery Algorithms for Cancer Gene Expression Profile

open access: yesIEEE Access, 2019
Several hybrid gene selection algorithms for cancer classification that employ bio-inspired evolutionary wrapper algorithm have been proposed in the literature and show good classification accuracy.
Nada Almugren, Hala M. Alshamlan
doaj   +1 more source

Natural selection and gene substitution

open access: yesGenetical Research, 1969
Using models which describe the change, by natural selection, of the actual numbers of genes rather than their relative frequencies, it is demonstrated that the equation familiar to geneticists, i.e.dp/dt=sp(1 −p), is appropriate under a wide range of circumstances.
M, Kimura, J F, Crow
openaire   +2 more sources

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