Results 51 to 60 of about 1,213,334 (312)

Marker assisted selection with optimised contributions of the candidates to selection [PDF]

open access: yes, 2002
The benefits of marker assisted selection (MAS) are evaluated under realistic assumptions in schemes where the genetic contributions of the candidates to selection are optimised for maximising the rate of genetic progress while restricting the ...
Ricardo Pong-Wong   +14 more
core   +1 more source

Species versus gene selection [PDF]

open access: yesGenetics Selection Evolution, 1989
Author(s): Tsakas, S. C. | Abstract: Species selection has been recently promoted (Gould a Eldredge, 1988a, 1988b) as the driving force in macroevolution, and viewed as an explanation for the variability in rates observed, both temporally and spatially, at the phenotypic level. This has rekindled the contention between microevolutionists (Maynard Smith,
openaire   +5 more sources

A Gene Selection Method for Cancer Classification [PDF]

open access: yesComputational and Mathematical Methods in Medicine, 2012
This paper proposes a method to select a set of genes from a large number of genes with the ability of classifying types of diseases. The proposed gene selection method is designed according to correlation analysis and the concept of 95% reference range. The method is very simple and uses the information of all genes.
Xiaodong Wang 0003, Jun Tian
openaire   +2 more sources

Large-scale attribute selection using wrappers [PDF]

open access: yes, 2009
Scheme-specific attribute selection with the wrapper and variants of forward selection is a popular attribute selection technique for classification that yields good results. However, it can run the risk of overfitting because of the extent of the search
Andreas Karwath   +8 more
core   +1 more source

Genes, individuals, and kin selection [PDF]

open access: yesProceedings of the National Academy of Sciences, 1981
The altruistic-gene theory of kin selection requires conditions so improbable that its reality is doubtful. The gene-quantity theory, including the theory of inclusive fitness, assumes that selection acts on sums of kins' genes, but no effective mechanism is apparent.
openaire   +2 more sources

Solving the riddle of codon usage preferences: a test for translational selection [PDF]

open access: yes, 2004
Translational selection is responsible for the unequal usage of synonymous codons in protein coding genes in a wide variety of organisms. It is one of the most subtle and pervasive forces of molecular evolution, yet, establishing the underlying causes ...
Savva, Renos   +2 more
core   +1 more source

Evaluation of gene selection metrics for tumor cell classification

open access: yesGenetics and Molecular Biology, 2004
Gene expression profiles contain the expression level of thousands of genes. Depending on the issue under investigation, this large amount of data makes analysis impractical. Thus, it is important to select subsets of relevant genes to work with.
Katti Faceli   +2 more
doaj   +1 more source

A Novel Method to Efficiently Highlight Nonlinearly Expressed Genes

open access: yesFrontiers in Genetics, 2020
For precision medicine, there is a need to identify genes that accurately distinguish the physiological state or response to a particular therapy, but this can be challenging.
Qifei Wang   +7 more
doaj   +1 more source

Hybrid Symmetrical Uncertainty and Reference Set Harmony Search Algorithm for Gene Selection Problem

open access: yesMathematics, 2022
Selecting the most miniature possible set of genes from microarray datasets for clinical diagnosis and prediction is one of the most challenging machine learning tasks. A robust gene selection technique is required to identify the most significant subset
Salam Salameh Shreem   +3 more
doaj   +1 more source

Natural selection and gene substitution

open access: yesGenetical Research, 1969
Using models which describe the change, by natural selection, of the actual numbers of genes rather than their relative frequencies, it is demonstrated that the equation familiar to geneticists, i.e.dp/dt=sp(1 −p), is appropriate under a wide range of circumstances.
M, Kimura, J F, Crow
openaire   +2 more sources

Home - About - Disclaimer - Privacy