Results 51 to 60 of about 2,179,747 (304)

Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae [PDF]

, 2015
OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Alexander W. Tucker, Andrew N. Rycroft, Brendan W. Wren, Clinical and Laboratory Standards Institute, de Groot, Duncan J. Maskell, Janine T. Bossé, Jon Rogers, Lucy A. Weinert, Matt T. G. Holden, Olusegun Oshota, Paul R. Langford, Roberto Fernandez Crespo, Roy R. Chaudhuri, Stephanie Walker, Susanna M. Williamson, Tom Atherton, Yanwen Li   +17 more
core   +4 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Opportunities for genetic research in otology: a review of the literature

Лечащий Врач
Background. Because of the serious psychological, social, economic, and medical consequences, considerable effort has been invested in identifying genes and molecular pathways involved in hearing loss to prevent, improve rehabilitation, and develop ...
E. A. Shulepova, A. A. Nidelko
doaj   +1 more source

Genetic Abnormalities, Clonal Evolution, and Cancer Stem Cells of Brain Tumors

Medical Sciences, 2018
Brain tumors are highly heterogeneous and have been classified by the World Health Organization in various histological and molecular subtypes. Gliomas have been classified as ranging from low-grade astrocytomas and oligodendrogliomas to high-grade ...
Ugo Testa, Germana Castelli, Elvira Pelosi   +2 more
doaj   +1 more source

SPsimSeq : semi-parametric simulation of bulk and single-cell RNA-sequencing data [PDF]

, 2020
SPsimSeq is a semi-parametric simulation method to generate bulk and single-cell RNA-sequencing data. It is designed to simulate gene expression data with maximal retention of the characteristics of real data.
Assefa, Alemu Takele, Thas, Olivier, Vandesompele, Jo   +2 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Factors influencing the spatial distributions of river microbial communities at the watershed scale: a case study involving the Wuding River Basin

Frontiers in Microbiology
Microbial communities regulate water quality and biogeochemical cycling in rivers, but their responses to geomorphological factors remain unclear. Water samples were collected in August 2024 (summer wet season) from the Wuding River, and metagenomic ...
Nan Xue, Nan Xue, Nan Xue, Manhong Xia, Manhong Xia, Manhong Xia, Bo Hu, Xinru Gong, Zhoufeng Wang, Zhoufeng Wang, Zhoufeng Wang, Xiaohong Zhao, Xiaohong Zhao   +12 more
doaj   +1 more source

Exploring genome wide bisulfite sequencing for DNA methylation analysis in livestock: a technical assessment [PDF]

, 2014
peer-reviewedRecent advances made in “omics” technologies are contributing to a revolution in livestock selection and breeding practices. Epigenetic mechanisms, including DNA methylation are important determinants for the control of gene expression in ...
Couldrey, Christine, Doherty, Rachael
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Fluoroquinolone and Second-Line Injectable Resistance Among Rifampicin- and Isoniazid-Resistant Mycobacterium tuberculosis Clinical Isolates: A Molecular Study from a High-Burden Setting

Microorganisms
Drug-resistant tuberculosis (DR-TB) threatens global TB control. We investigated the prevalence and molecular characteristics of second-line drug resistance among rifampicin (RIF)- and/or isoniazid (INH)-resistant Mycobacterium tuberculosis complex (MTBC)
Rosângela Siqueira Oliveira, Angela Pires Brandao, Fabiane Maria de Almeida Ferreira, Sonia Maria da Costa, Vera Lucia Maria Silva, Lucilaine Ferrazoli, Erica Chimara, Juliana Maira Watanabe Pinhata   +7 more
doaj   +1 more source