Results 51 to 60 of about 631,661 (355)
Cancer Cell International, 2020 Background Bladder cancer is one of the most prevalent malignancies worldwide. However, traditional indicators have limited predictive effects on the clinical outcomes of bladder cancer.
Chen Zhang +4 more
doaj +1 more source
Super-paramagnetic clustering of yeast gene expression profiles [PDF]
, 1999 High-density DNA arrays, used to monitor gene expression at a genomic scale, have produced vast amounts of information which require the development of efficient computational methods to analyze them.
Alon +21 more
core +6 more sources
Frontiers in ImmunologyBackgroundThe prognosis of hepatocellular carcinoma (HCC) remains challenging, and immune activation plays a critical role in cancer treatment. Identifying reliable immune activation-related prognostic markers is critical for predicting HCC patient ...
Xiaofeng Wang +3 more
doaj +1 more source
Frontiers in Genetics, 2020 BackgroundDespite recent advance in immune therapy, great heterogeneity exists in the outcomes of colorectal cancer (CRC) patients. In this study, we aimed to analyze the immune-related gene (IRG) expression profiles from three independent public ...
Siqi Dai +6 more
doaj +1 more source
A Novel Ferroptosis-Associated Gene Signature to Predict Prognosis in Patients with Uveal Melanoma
Diagnostics, 2021 Background: Uveal melanoma (UM) is the most common intraocular tumor in adults. Ferroptosis is a newly recognized process of cell death, which is different from other forms of cell death in terms of morphology, biochemistry and genetics, and has played a
Huan Luo, Chao Ma
doaj +1 more source
A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity [PDF]
, 2014 Introduction: There is an unmet clinical need for biomarkers to identify breast cancer patients at an increased risk of developing brain metastases. The objective is to identify gene signatures and biological pathways associated with human epidermal ...
Akbari, Mohammad R +13 more
core +1 more source
Gene expression signature in transplantation tolerance
Clinica Chimica Acta, 2012 Human kidney transplantation tolerance exists, but the definition of true tolerance as defined by Billingham and colleagues suffers several key elements that cannot be demonstrated in humans. Indeed, human tolerance in transplantation is defined by different functional and clinical parameters, this is why in clinical transplantation we preferentially ...
Sophie Brouard +3 more
openaire +4 more sources
EBioMedicine, 2018 Background: Hypoxia is associated with a poor prognosis in prostate cancer. This work aimed to derive and validate a hypoxia-related mRNA signature for localized prostate cancer.
Lingjian Yang +27 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 BackgroundIncreasing evidence has shown that hypoxia microenvironment relates to tumor initiation and progression. However, no studies focus on the application of hypoxia-associated genes in predicting osteosarcoma patients’ prognosis. This research aims
Yucheng Fu +8 more
doaj +1 more source
A Robust Gene Expression Prognostic Signature for Overall Survival in High-Grade Serous Ovarian Cancer. [PDF]
, 2019 The objective of this research was to develop a robust gene expression-based prognostic signature and scoring system for predicting overall survival (OS) of patients with high-grade serous ovarian cancer (HGSOC).
Hang, Bo +8 more
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