Results 31 to 40 of about 320,196 (265)

Signature of arylacetamide deacetylase expression is associated with prognosis and immune infiltration in ovarian cancer [PDF]

Obstetrics & Gynecology Science, 2022
Objective The role of the protein-coding gene arylacetamide deacetylase (AADAC) in the prognostication of ovarian cancer remains uncertain. We aimed to identify and validate its prognostic value using integrated bioinformatics analyses.
Jianyang Feng, Hong He
doaj   +1 more source

Identification and Validation of an 11-Ferroptosis Related Gene Signature and Its Correlation With Immune Checkpoint Molecules in Glioma

Frontiers in Cell and Developmental Biology, 2021
BackgroundGlioma is the most common primary malignant brain tumor with significant mortality and morbidity. Ferroptosis, a novel form of programmed cell death (PCD), is critically involved in tumorigenesis, progression and metastatic processes.MethodsWe ...
Zhuohui Chen, Tong Wu, Zhouyi Yan, Mengqi Zhang   +3 more
doaj   +1 more source

Development and Validation of an E2F-Related Gene Signature to Predict Prognosis of Patients With Lung Squamous Cell Carcinoma

Frontiers in Oncology, 2021
BackgroundLung squamous cell carcinoma (LUSC) generally correlates with poor clinical prognoses due to the lack of available prognostic biomarkers. This study is designed to identify a potential biomarker significant for the prognosis and treatment of ...
Cailian Wang, Xuyu Gu, Xiuxiu Zhang, Min Zhou, Yan Chen   +4 more
doaj   +1 more source

Systematic establishment and verification of an epithelial-mesenchymal transition gene signature for predicting prognosis of oral squamous cell carcinoma

Frontiers in Genetics, 2023
Objective: Epithelial-mesenchymal transition (EMT) is linked to an unfavorable prognosis in oral squamous cell carcinoma (OSCC). Here, we aimed to develop an EMT gene signature for OSCC prognosis.Methods: In TCGA dataset, prognosis-related EMT genes with
Jun Ai, Yaqin Tan, Bo Liu, Yuhong Song, Yanqin Wang, Xin Xia, Qicheng Fu   +6 more
doaj   +1 more source

A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer

Cancer Cell International, 2020
Background Bladder cancer is one of the most prevalent malignancies worldwide. However, traditional indicators have limited predictive effects on the clinical outcomes of bladder cancer.
Chen Zhang, Xin Gou, Weiyang He, Huaan Yang, Hubin Yin   +4 more
doaj   +1 more source

A Novel Seven Gene Signature-Based Prognostic Model to Predict Distant Metastasis of Lymph Node-Negative Triple-Negative Breast Cancer

Frontiers in Oncology, 2021
BackgroundThe prognosis of lymph node-negative triple-negative breast cancer (TNBC) is still worse than that of other subtypes despite adjuvant chemotherapy.
Wenting Peng, Wenting Peng, Wenting Peng, Wenting Peng, Caijin Lin, Caijin Lin, Caijin Lin, Shanshan Jing, Shanshan Jing, Guanhua Su, Guanhua Su, Guanhua Su, Xi Jin, Xi Jin, Xi Jin, Genhong Di, Genhong Di, Genhong Di, Zhiming Shao, Zhiming Shao, Zhiming Shao   +20 more
doaj   +1 more source

An immune cell activation signature reflected hepatocellular carcinoma heterogeneity and predicted clinical outcomes

Frontiers in Immunology
BackgroundThe prognosis of hepatocellular carcinoma (HCC) remains challenging, and immune activation plays a critical role in cancer treatment. Identifying reliable immune activation-related prognostic markers is critical for predicting HCC patient ...
Xiaofeng Wang, Dongli Liu, Shuai Wang, Rui He   +3 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Identification of an Immune-Related Gene Signature to Improve Prognosis Prediction in Colorectal Cancer Patients

Frontiers in Genetics, 2020
BackgroundDespite recent advance in immune therapy, great heterogeneity exists in the outcomes of colorectal cancer (CRC) patients. In this study, we aimed to analyze the immune-related gene (IRG) expression profiles from three independent public ...
Siqi Dai, Siqi Dai, Shuang Xu, Yao Ye, Yao Ye, Kefeng Ding, Kefeng Ding   +6 more
doaj   +1 more source

An immune cell infiltration-related gene signature predicts prognosis for bladder cancer

Scientific Reports, 2021
To explore novel therapeutic targets, develop a gene signature and construct a prognostic nomogram of bladder cancer (BCa). Transcriptome data and clinical traits of BCa were downloaded from UCSC Xena database and Gene Expression Omnibus (GEO) database ...
Hualin Chen, Yang Pan, Xiaoxiang Jin, Gang Chen   +3 more
doaj   +1 more source