Results 41 to 50 of about 3,125,604 (306)

Identification and Validation of an 11-Ferroptosis Related Gene Signature and Its Correlation With Immune Checkpoint Molecules in Glioma

Frontiers in Cell and Developmental Biology, 2021
BackgroundGlioma is the most common primary malignant brain tumor with significant mortality and morbidity. Ferroptosis, a novel form of programmed cell death (PCD), is critically involved in tumorigenesis, progression and metastatic processes.MethodsWe ...
Zhuohui Chen, Tong Wu, Zhouyi Yan, Mengqi Zhang   +3 more
doaj   +1 more source

Large-scale identification of pathogenicity factors in "Bartonella" by signature-tagged mutagenesis [PDF]

, 2005
Bartonellae are bacterial pathogens uniquely adapted to cause intraerythrocytic infection in their mammalian reservoir hosts. In the case of human-specific Bartonella bacilliformis and Bartonella quintana, the intraerythrocytic bacteremia leads to the ...
Saenz Dürrmeier, Luis-Henri
core   +1 more source

DataSheet_1_Identification of a Four-Gene-Based SERM Signature for Prognostic and Drug Sensitivity Prediction in Gastric Cancer.zip

, 2022
BackgroundGastric cancer (GC) is a highly molecular heterogeneous tumor with poor prognosis. Epithelial-mesenchymal transition (EMT) process and cancer stem cells (CSCs) are reported to share common signaling pathways and cause poor prognosis in GC ...
Xiya Jia (11936588), Wanjing Feng (11936597), Siyuan Chen (200219), Hui Zhu (87035), Bing Chen (32669), Ziteng Li (11936591), Shenglin Huang (123385), Runye Zhou (11936594), Xiaodong Zhu (229321)   +8 more
core   +1 more source

Development and Validation of an E2F-Related Gene Signature to Predict Prognosis of Patients With Lung Squamous Cell Carcinoma

Frontiers in Oncology, 2021
BackgroundLung squamous cell carcinoma (LUSC) generally correlates with poor clinical prognoses due to the lack of available prognostic biomarkers. This study is designed to identify a potential biomarker significant for the prognosis and treatment of ...
Cailian Wang, Xuyu Gu, Xiuxiu Zhang, Min Zhou, Yan Chen   +4 more
doaj   +1 more source

Systematic establishment and verification of an epithelial-mesenchymal transition gene signature for predicting prognosis of oral squamous cell carcinoma

Frontiers in Genetics, 2023
Objective: Epithelial-mesenchymal transition (EMT) is linked to an unfavorable prognosis in oral squamous cell carcinoma (OSCC). Here, we aimed to develop an EMT gene signature for OSCC prognosis.Methods: In TCGA dataset, prognosis-related EMT genes with
Jun Ai, Yaqin Tan, Bo Liu, Yuhong Song, Yanqin Wang, Xin Xia, Qicheng Fu   +6 more
doaj   +1 more source

A quantitative account of genomic island acquisitions in prokaryotes [PDF]

, 2011
Background Microbial genomes do not merely evolve through the slow accumulation of mutations, but also, and often more dramatically, by taking up new DNA in a process called horizontal gene transfer.
van Passel, Mark W. J., van Passel Mark WJ, Passel, M.W.J., van, Mark WJ van Passel, Roos Tom E, Roos, T.E., van Passel, M.W.J., Roos, Tom E., Tom E Roos   +8 more
core   +3 more sources

A Novel Seven Gene Signature-Based Prognostic Model to Predict Distant Metastasis of Lymph Node-Negative Triple-Negative Breast Cancer

Frontiers in Oncology, 2021
BackgroundThe prognosis of lymph node-negative triple-negative breast cancer (TNBC) is still worse than that of other subtypes despite adjuvant chemotherapy.
Wenting Peng, Wenting Peng, Wenting Peng, Wenting Peng, Caijin Lin, Caijin Lin, Caijin Lin, Shanshan Jing, Shanshan Jing, Guanhua Su, Guanhua Su, Guanhua Su, Xi Jin, Xi Jin, Xi Jin, Genhong Di, Genhong Di, Genhong Di, Zhiming Shao, Zhiming Shao, Zhiming Shao   +20 more
doaj   +1 more source

A glycolysis-based 4-mRNA signature correlates with the prognosis and cell cycle process in patients with bladder cancer

Cancer Cell International, 2020
Background Bladder cancer is one of the most prevalent malignancies worldwide. However, traditional indicators have limited predictive effects on the clinical outcomes of bladder cancer.
Chen Zhang, Xin Gou, Weiyang He, Huaan Yang, Hubin Yin   +4 more
doaj   +1 more source

Identification of an Immune-Related Gene Signature to Improve Prognosis Prediction in Colorectal Cancer Patients

Frontiers in Genetics, 2020
BackgroundDespite recent advance in immune therapy, great heterogeneity exists in the outcomes of colorectal cancer (CRC) patients. In this study, we aimed to analyze the immune-related gene (IRG) expression profiles from three independent public ...
Siqi Dai, Siqi Dai, Shuang Xu, Yao Ye, Yao Ye, Kefeng Ding, Kefeng Ding   +6 more
doaj   +1 more source

Development and Validation of a Hypoxia-Associated Prognostic Signature Related to Osteosarcoma Metastasis and Immune Infiltration

Frontiers in Cell and Developmental Biology, 2021
BackgroundIncreasing evidence has shown that hypoxia microenvironment relates to tumor initiation and progression. However, no studies focus on the application of hypoxia-associated genes in predicting osteosarcoma patients’ prognosis. This research aims
Yucheng Fu, Qiyuan Bao, Zhuochao Liu, Guoyu He, Junxiang Wen, Qi Liu, Yiqi Xu, Zhijian Jin, Weibin Zhang   +8 more
doaj   +1 more source