Results 211 to 220 of about 7,203,409 (405)

Engineered microRNA scaffolds for potent gene silencing in vivo. [PDF]

Sci Rep
Militello G, Greig A, Bi C, Vasileva A, Zavodszky MI, Lo SC, Guilmette E, Clarner P, Liu B, Bhat G, Suh J, Dow L, Zuber J, Fellmann C, Premsrirut PK.   +14 more
europepmc   +1 more source

Mum's the Word: MOM and Modifiers of Transcriptional Gene Silencing [PDF]

, 2000
Trevor Stokes, Eric J. Richards
openalex   +1 more source

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

[Retracted] Effects of TLR4 gene silencing on the proliferation and apotosis of hepatocarcinoma HEPG2 cells. [PDF]

Oncol Lett
Liu Y, Li T, Xu Y, Xu E, Zhou M, Wang B, Shen J.   +6 more
europepmc   +1 more source

Vibrio cholerae H-NS Silences Virulence Gene Expression at Multiple Steps in the ToxR Regulatory Cascade

, 2000
Melinda B. Nye, James Pfau, Karen Skorupski, Ronald K. Taylor   +3 more
openalex   +1 more source

Trans‐regulated Silencing and Reactivation of TP53 Tumor Suppressor Gene in Malignant Transformation and Its Reversion [PDF]

, 2000
Lichun Yang, Masao S. Sasaki
openalex   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Multiplex engineering using microRNA-mediated gene silencing in CAR T cells. [PDF]

Front Immunol
Golinelli G, Scholler J, Roussel-Gervais A, Šakić A, Ilmjärv S, Song D, Gabunia K, Ji M, Fan TJ, Gupta A, Deshmukh M, Berjis A, Cuoghi Costantini R, Apodaca K, Sheppard NC, Kili S, Dominici M, Alessandrini M, June CH, Levine BL.   +19 more
europepmc   +1 more source

Molecular Determinants for Targeting Heterochromatin Protein 1-Mediated Gene Silencing: Direct Chromoshadow Domain–KAP-1 Corepressor Interaction Is Essential

, 2000
Mark S. Lechner, Gillian E. Begg, David W. Speicher, Frank J. Rauscher   +3 more
openalex   +1 more source

Phenotypic Instability and Rapid Gene Silencing in Newly Formed Arabidopsis Allotetraploids [PDF]

, 2000
Luca Comai, Anand P. Tyagi, Ken Winter, Rachel Holmes‐Davis, Steven H. Reynolds, Yvonne Y. Stevens, Breck Byers   +6 more
openalex   +1 more source