Results 51 to 60 of about 6,519,783 (149)
NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model
Background Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM).
Bei-bei Luo+8 more
semanticscholar +1 more source
Cassava geminivirus agroclones for virus-induced gene silencing in cassava leaves and roots
Aim We report the construction of a Virus-Induced Gene Silencing (VIGS) vector and an agroinoculation protocol for gene silencing in cassava (Manihot esculenta Crantz) leaves and roots.
Ezequiel Matias Lentz+8 more
doaj +1 more source
Efficient programmable gene silencing by Cascade
Methods that permit controlled changes in the expression of genes are important tools for biological and medical research, and for biotechnological applications.
D. Rath+4 more
semanticscholar +1 more source
Targeting fungal genes by diced siRNAs: a rapid tool to decipher gene function in Aspergillus nidulans. [PDF]
BACKGROUND: Gene silencing triggered by chemically synthesized small interfering RNAs (siRNAs) has become a powerful tool for deciphering gene function in many eukaryotes.
Natarajaswamy Kalleda+2 more
doaj +1 more source
Lentivirus-delivered stable gene silencing by RNAi in primary cells.
Genome-wide genetic approaches have proven useful for examining pathways of biological significance in model organisms such as Saccharomyces cerevisiae, Drosophila melanogastor, and Caenorhabditis elegans, but similar techniques have proven difficult to ...
S. Stewart+11 more
semanticscholar +1 more source
Highly Specific Gene Silencing by Artificial MicroRNAs in Arabidopsis[W][OA]
Plant microRNAs (miRNAs) affect only a small number of targets with high sequence complementarity, while animal miRNAs usually have hundreds of targets with limited complementarity.
R. Schwab+4 more
semanticscholar +1 more source
Over the last decade, several studies have revealed the enormous potential of RNA-silencing strategies as a potential alternative to conventional pesticides for plant protection.
Bernhard Timo Werner+4 more
doaj +1 more source
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
Nibedita Patel+6 more
doaj +1 more source
A dual gene-silencing vector system for monocot and dicot plants.
Plant virus-based gene-silencing vectors have been extensively and successfully used to elucidate functional genomics in plants. However, only limited virus-induced gene-silencing (VIGS) vectors can be used in both monocot and dicot plants.
M. Liou+4 more
semanticscholar +1 more source
Tobacco rattle virus (TRV) has a bipartite, positive-sense single-stranded RNA genome and is widely used for virus-induced gene silencing (VIGS) in plants.
Xianbao Deng+6 more
doaj +1 more source