Results 51 to 60 of about 6,519,783 (149)

NLRP3 Gene Silencing Ameliorates Diabetic Cardiomyopathy in a Type 2 Diabetes Rat Model

open access: yesPLoS ONE, 2014
Background Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome is associated with metabolic disorder and cell death, which are important triggers in diabetic cardiomyopathy (DCM).
Bei-bei Luo   +8 more
semanticscholar   +1 more source

Cassava geminivirus agroclones for virus-induced gene silencing in cassava leaves and roots

open access: yesPlant Methods, 2018
Aim We report the construction of a Virus-Induced Gene Silencing (VIGS) vector and an agroinoculation protocol for gene silencing in cassava (Manihot esculenta Crantz) leaves and roots.
Ezequiel Matias Lentz   +8 more
doaj   +1 more source

Efficient programmable gene silencing by Cascade

open access: yesNucleic Acids Research, 2014
Methods that permit controlled changes in the expression of genes are important tools for biological and medical research, and for biotechnological applications.
D. Rath   +4 more
semanticscholar   +1 more source

Targeting fungal genes by diced siRNAs: a rapid tool to decipher gene function in Aspergillus nidulans. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Gene silencing triggered by chemically synthesized small interfering RNAs (siRNAs) has become a powerful tool for deciphering gene function in many eukaryotes.
Natarajaswamy Kalleda   +2 more
doaj   +1 more source

Lentivirus-delivered stable gene silencing by RNAi in primary cells.

open access: yesRNA: A publication of the RNA Society, 2003
Genome-wide genetic approaches have proven useful for examining pathways of biological significance in model organisms such as Saccharomyces cerevisiae, Drosophila melanogastor, and Caenorhabditis elegans, but similar techniques have proven difficult to ...
S. Stewart   +11 more
semanticscholar   +1 more source

Highly Specific Gene Silencing by Artificial MicroRNAs in Arabidopsis[W][OA]

open access: yesThe Plant Cell Online, 2006
Plant microRNAs (miRNAs) affect only a small number of targets with high sequence complementarity, while animal miRNAs usually have hundreds of targets with limited complementarity.
R. Schwab   +4 more
semanticscholar   +1 more source

RNA-Spray-Mediated Silencing of Fusarium graminearum AGO and DCL Genes Improve Barley Disease Resistance

open access: yesFrontiers in Plant Science, 2020
Over the last decade, several studies have revealed the enormous potential of RNA-silencing strategies as a potential alternative to conventional pesticides for plant protection.
Bernhard Timo Werner   +4 more
doaj   +1 more source

Erratum: miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin

open access: yesScientific Reports, 2017
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
Nibedita Patel   +6 more
doaj   +1 more source

A dual gene-silencing vector system for monocot and dicot plants.

open access: yesPlant Biotechnology Journal, 2014
Plant virus-based gene-silencing vectors have been extensively and successfully used to elucidate functional genomics in plants. However, only limited virus-induced gene-silencing (VIGS) vectors can be used in both monocot and dicot plants.
M. Liou   +4 more
semanticscholar   +1 more source

Modification of Tobacco rattle virus RNA1 to Serve as a VIGS Vector Reveals That the 29K Movement Protein Is an RNA Silencing Suppressor of the Virus

open access: yesMolecular Plant-Microbe Interactions, 2013
Tobacco rattle virus (TRV) has a bipartite, positive-sense single-stranded RNA genome and is widely used for virus-induced gene silencing (VIGS) in plants.
Xianbao Deng   +6 more
doaj   +1 more source

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