Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development. [PDF]
Lan S. Chen+3 more
openalex +1 more source
A method for overproduction of a protein of a target gene in Escherichia coli.
Tatsurou Shibui+2 more
openalex +2 more sources
Adjacent pol II and pol III promoters: transcription of the yeast retrotransposon Ty3 and a target tRNA gene [PDF]
Philip T. Kinsey, Suzanne Sandmeyer
openalex +1 more source
Study of the homologous recombination genetic system to improve genetic transformation of wheat
A. De Bustos, R. Pérez, N. Jouve
doaj +1 more source
Advancing Gene Selection in Oncology: A Fusion of Deep Learning and Sparsity for Precision Gene Selection [PDF]
Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep learning-based survival prediction models.
arxiv
Phosphorylation enhances the target gene sequence-dependent dimerization of thyroid hormone receptor with retinoid X receptor. [PDF]
Manoj K. Bhat+2 more
openalex +1 more source
DeepGDel: Deep Learning-based Gene Deletion Prediction Framework for Growth-Coupled Production in Genome-Scale Metabolic Models [PDF]
In genome-scale constraint-based metabolic models, gene deletion strategies are crucial for achieving growth-coupled production, where cell growth and target metabolite production are simultaneously achieved. While computational methods for calculating gene deletions have been widely explored and contribute to developing gene deletion strategy ...
arxiv
Modulation of gene activity by consecutive gene targeting of one creatine kinase M allele in mouse embryonic stem cells [PDF]
Jan van Deursen+4 more
openalex +1 more source
ScAtt: an Attention based architecture to analyze Alzheimer's disease at cell type level from single-cell RNA-sequencing data [PDF]
Alzheimer's disease (AD) is a pervasive neurodegenerative disorder that leads to memory and behavior impairment severe enough to interfere with daily life activities. Understanding this disease pathogenesis can drive the development of new targets and strategies to prevent and treat AD.
arxiv