Results 231 to 240 of about 12,501,640 (402)

Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor α chain gene

, 1993
David Dombrowicz, Véronique Flamand, Kristen K. Brigman, Beverly H. Koller, Jean-Pierre Kinet   +4 more
openalex   +1 more source

Modulation of gene activity by consecutive gene targeting of one creatine kinase M allele in mouse embryonic stem cells [PDF]

, 1991
Jan van Deursen, Robin Lovell‐Badge, Frank Oerlemans, Jan Schepens, Bé Wieringa   +4 more
openalex   +1 more source

Targeted gene repair [PDF]

Gene Therapy, 1999
openaire   +3 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Homology-arm length of donor DNA affects the impact of Msh2 loss on homologous recombination-mediated gene targeting. [PDF]

Proc Natl Acad Sci U S A
Saito S, Suzuki T, Nohmi T, Adachi N.
europepmc   +1 more source

Gene targeting in polymerase theta-deficient Arabidopsis thaliana. [PDF]

Plant J, 2022
van Tol N, van Schendel R, Bos A, van Kregten M, de Pater S, Hooykaas PJJ, Tijsterman M.   +6 more
europepmc   +1 more source

Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization.

, 1994
Tsukasa Baba, Sadahiro Azuma, Shin‐ichi Kashiwabara, Yutaka Toyoda   +3 more
openalex   +1 more source

Visceral targets specify calcitonin gene-related peptide and substance P enrichment in trigeminal afferent projections [PDF]

, 1992
Kieran Horgan, Derek van der Kooy
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Beyond a few bases: methods for large DNA insertion and gene targeting in plants. [PDF]

Plant J
Vollen K, Alonso JM, Stepanova AN.
europepmc   +1 more source