Results 121 to 130 of about 1,824,389 (266)

A Cancer Biotherapy Resource [PDF]

open access: yesarXiv, 2015
Cancer Biotherapy (CB), as opposed to cancer chemotherapy, is the use of macromolecular, biological agents instead of organic chemicals or drugs to treat cancer. Biological agents usually have higher selectivity and have less toxic side effects than chemical agents. The I.S.B.T.C., being the only major information database for CB, seems lacking in some
arxiv  

Nanostructured lipid carriers for MicroRNA delivery in tumor gene therapy

open access: yesCancer Cell International, 2018
MicroRNAs (miRNAs), which are endogenous about 20–23 nucleotides non-coding RNAs, have been acted as post-transcriptional regulators of gene expression.
Hairong Wang   +8 more
doaj   +1 more source

Use of integrase-minus lentiviral vector for transient expression [PDF]

open access: yes, 2012
Objective: Lentivirus-derived vectors are among the most promising viral vectors for gene therapy which is currently available, but their use in clinical practice is limited due to associated risk of insertional mutagenesis.
Azadeh, H.   +5 more
core   +2 more sources

Gene therapy in keratoconus

open access: yesOman Journal of Ophthalmology, 2015
Keratoconus (KC) is the most common ectasia of the cornea and is a common reason for corneal transplant. Therapeutic strategies that can arrest the progression of this disease and modify the underlying pathogenesis are getting more and more popularity among scientists.
Mohammad Naderan   +2 more
openaire   +4 more sources

Advancing Gene Selection in Oncology: A Fusion of Deep Learning and Sparsity for Precision Gene Selection [PDF]

open access: yesarXiv
Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep learning-based survival prediction models.
arxiv  

Gene therapy:the potential applicability of gene transfer technology to the human germline [PDF]

open access: yes, 2004
The theoretical possibility of applying gene transfer methodologies to the human germline is explored. Transgenic methods for genetically manipulating embryos may in principle be applied to humans.
Smith, Kevin R.
core   +2 more sources

Identifying Key Genes in Cancer Networks Using Persistent Homology [PDF]

open access: yesarXiv
Identifying driver genes is crucial for understanding oncogenesis and developing targeted cancer therapies. Driver discovery methods using protein or pathway networks rely on traditional network science measures, focusing on nodes, edges, or community metrics.
arxiv  

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