Results 61 to 70 of about 1,204,526 (212)

Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC

Disease Models & Mechanisms, 2016
Mucopolysaccharidosis type IIIC (MPSIIIC) is a severe lysosomal storage disease caused by deficiency in activity of the transmembrane enzyme heparan-α-glucosaminide N-acetyltransferase (HGSNAT) that catalyses the N-acetylation of α-glucosamine residues ...
Sara Marcó, Anna Pujol, Carles Roca, Sandra Motas, Albert Ribera, Miguel Garcia, Maria Molas, Pilar Villacampa, Cristian S. Melia, Víctor Sánchez, Xavier Sánchez, Joan Bertolin, Jesús Ruberte, Virginia Haurigot, Fatima Bosch   +14 more
doaj   +1 more source

Gene therapy of gastric cancer using LIGHT-secreting human umbilical cord blood-derived mesenchymal stem cells [PDF]

, 2012
Xinhong Zhu, Dongming Su, Shiying Xuan, Guiliang Ma, Zhenbo Dai, Tongyun Liu, Dongqi Tang, Weizheng Mao, Chenfang Dong   +8 more
openalex   +1 more source

The joint battle to tackle epidermolysis bullosa through gene therapy

, 2022
Laura De Rosa, Michele De Luca
openalex   +2 more sources

Development of convolutional neural networks for automated brain-wide histopathological analysis in mouse models of synucleinopathies

npj Parkinson's Disease
Preclinical animal models are indispensable for uncovering disease mechanisms and developing novel therapeutic interventions in synucleinopathies. Key readouts including neuronal cell death, neuroinflammation and alpha-synuclein protein aggregation, are ...
A. Barber-Janer, E. Van Acker, E. Vonck, D. Plessers, F. Rosada, C. Van den Haute, V. Baekelandt, W. Peelaerts   +7 more
doaj   +1 more source

Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy

Frontiers in Medicine, 2023
Reetta A. E. Eriksson, Reetta A. E. Eriksson, Tiina Nieminen, Lionel Galibert, Sanna K. Peltola, Petra Tikkanen, Piia Käyhty, Piia Käyhty, Hanna M. Leinonen, Igor Oruetxebarria, Saana Lepola, Anniina J. Valkama, Eevi M. Lipponen, Hanna P. Lesch, Seppo Ylä-Herttuala, Seppo Ylä-Herttuala, Kari J. Airenne   +16 more
doaj   +1 more source

Systemic RALA/iNOS Nanoparticles: A Potent Gene Therapy for Metastatic Breast Cancer Coupled as a Biomarker of Treatment [PDF]

, 2017
Cian M. McCrudden, J.W. McBride, Joanne McCaffrey, Ahlam Ali, Nicholas Dunne, Victoria Kett, Jonathan A. Coulter, Tracy Robson, Helen O. McCarthy   +8 more
openalex   +1 more source

A preliminary study of Parkinson’s gene therapy via sono-magnetic sensing gene vector for conquering extra/intracellular barriers in mice

, 2020
Chun-Yao Wu, Rih-Yang Huang, En-Chi Liao, Yu‐Chun Lin, Yi-Ju Ho, Chien‐Wen Chang, Hong‐Lin Chan, Ying‐Zu Huang, Tsung-Hsun Hsieh, Ching‐Hsiang Fan, Chih‐Kuang Yeh   +10 more
openalex   +1 more source

Approved gene therapies in Australia: coming to a store near you

, 2022
Shreyashee Mallik, Charles G. Bailey, John E.J. Rasko   +2 more
openalex   +1 more source

Combined anti-tumor necrosis factor-α therapy and DMARD therapy in rheumatoid arthritis patients reduces inflammatory gene expression in whole blood compared to DMARD therapy alone [PDF]

, 2012
Carl K. Edwards
openalex   +1 more source

The Cancer/Testis Antigen CT45A1 Promotes Transcription of Oncogenic Sulfatase-2 Gene in Breast Cancer Cells and Is Sensible Targets for Cancer Therapy

, 2023
Ping Yang, Yingnan Qiao, Huaidong Liao, Yizheng Huang, Mei Meng, Yu Chen, Quansheng Zhou   +6 more
openalex   +1 more source