Results 201 to 210 of about 1,686,914 (266)

H263A and SCAN1/H493R mutant TDP1 block TOP1-induced double-strand break repair during gene transcription in quiescent cells and promote cell death. [PDF]

Cell Death Dis
Rubio-Contreras D, Hidalgo-García D, Angulo-Jiménez C, Granado-Calle E, Sabio-Bonilla M, Ruiz JF, Gómez-Herreros F.   +6 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

The Regulatory Role of CTCF in IL6 Gene Transcription Assessed in Breast Cancer Cell Lines. [PDF]

Pharmaceuticals (Basel)
Pacheco-Hernandez AF, Rodriguez-Ramos I, Vazquez-Santillan K, Valle-Rios R, Velasco-Velázquez M, Aquino-Jarquin G, Martínez-Ruiz GU.   +6 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Mycorrhizal control of microbial gene transcription and taxonomic composition in the rhizosphere and bulk soil. [PDF]

ISME J
Wright F, Grand S, Sanders I, Arraiano-Castilho R.   +3 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Traffic light at DSB-transit regulation between gene transcription and DNA repair. [PDF]

FEBS Lett
Modafferi S, Esposito F, Tavella S, Gioia U, Francia S.   +4 more
europepmc   +1 more source

Malaria-derived hemozoin skews dendritic cell responses to bacterial infections by reducing interferon gene-transcription by SWI/SNF-NuRD. [PDF]

iScience
Lasaviciute G, Tariq K, Sugathan A, Quin J, Polenkowski M, Bujila I, Skorokhod O, Troye-Blomberg M, Sverremark-Ekström E, Östlund Farrants AK.   +9 more
europepmc   +1 more source

Dynamic interaction of MYC enhancer RNA with YEATS2 protein regulates MYC gene transcription in pancreatic cancer. [PDF]

EMBO Rep
Roy J, Kumar A, Chakravarty S, Biswas NK, Goswami S, Mazumder A.   +5 more
europepmc   +1 more source

Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking. [PDF]

Nat Commun
Farahbakhsh ZZ, Holleran KM, Sens JP, Fordahl SC, Mauterer MI, López AJ, Cuzon Carlson VC, Kiraly DD, Grant KA, Jones SR, Siciliano CA.   +10 more
europepmc   +1 more source