Results 221 to 230 of about 4,645,161 (307)

Adaptive gene transcription in Escherichia coli under environmental stress

Ge P, Rashid FM, Gaarthuis LKF, Cajili MKM, Tan M, Pang B, Schnetz K, Dame RT.   +7 more
europepmc   +1 more source

Correction: Novel drug-inducible CRISPRa/i systems for rapid and reversible manipulation of gene transcription. [PDF]

Cell Mol Life Sci
Sui M, Zhou M, Cui M, Liu H, Zhang X, Hu N, Li Y, Wang B, Yang G, Gui P, Zhu L, Wan F, Zhang B.   +12 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Central amygdala single-nucleus atlas reveals chromatin and gene transcription dynamics in human alcohol use disorder. [PDF]

Nat Commun
Lee CY, Hwang A, McRiley D, Lee J, Thibodeau G, Duman C, Zhang X, Skarica M, Coudriet J, Xu S, Terwilliger R, Sliby AN, Wang J, Nguyen T, Liu Y, Li H, Dai Y, Duan Z, Lei Y, Lin Y, Glausier JR, Lewis DA, Gelernter J, Holtzheimer PE, Xu K, Zhou H, Zhao H, Thompson SL, Krystal JH, Che A, Taylor JR, Zhang J, Girgenti MJ.   +32 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Nascent RNA profiling reveals genome-wide productive reiterative initiation regulating gene transcription in bacteria. [PDF]

Nucleic Acids Res
Sun Z, Huang G, Zhang Y, Wang S, Kashlev M.   +4 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Correction to 'TDG orchestrates ATF4-dependent gene transcription during retinoic acid-induced cell fate acquisition'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

Building hepatitis B virus gene transcription from the bottom up. [PDF]

Hepatology
Gómez-Moreno A, Bradley D, Ploss A.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source