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Horizontal Gene Transfer [PDF]
Evolution, Medicine, and Public Health, 2015 Horizontal gene transfer (HGT) is the movement of genetic information between organisms, a process that includes the spread of antibiotic resistance genes among bacteria (except for those from parent to offspring), fueling pathogen evolution.
A. R. Burmeister
semanticscholar +4 more sources
Inferring Horizontal Gene Transfer
PLOS Computational Biology, 2015 Horizontal or Lateral Gene Transfer (HGT or LGT) is the transmission of portions of genomic DNA between organisms through a process decoupled from vertical inheritance.
M. Ravenhall +3 more
semanticscholar +9 more sources
Current Biology, 2011 SummaryThe four disparate images shown in Figure 1 have this in common: each represents a radical adaptation that would not have happened had lateral gene transfer (LGT), also known as horizontal gene transfer (HGT), not been the powerful evolutionary force we now know it to be.
Olga Zhaxybayeva, W. Ford Doolittle
openaire +5 more sources
Horizontal Gene Transfer of Antibiotic Resistance Genes in Biofilms
Antibiotics, 2023 Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it hinders the treatment of infections with antibiotics due to the ...
C. Michaelis, E. Grohmann
semanticscholar +1 more source
Stable In-Planta Transformation System For Egyptian Sesame (Sesamum indicum L.) cv. Sohag 1
GM Crops & Food, 2023 Sesame (Sesamum indicum L.) is an important oil crop and one of the oldest-known oil crops to humankind. Sesame has excellent nutritional and therapeutic properties; it is rich in important fatty acids, protein, fiber, and vital minerals.
Esraa A. A. Sultan, Mohamed S. Tawfik
doaj +1 more source
Cells, 2023 Infantile parkinsonism-dystonia due to dopamine transporter deficiency syndrome (DTDS) is an ultrarare childhood movement disorder caused by biallelic loss-of-function mutations in the SLC6A3 gene.
Joanne Ng +3 more
doaj +1 more source
Immunomodulation in Administration of rAAV: Preclinical and Clinical Adjuvant Pharmacotherapies
Frontiers in Immunology, 2021 Recombinant adeno-associated virus (rAAV) has attracted a significant research focus for delivering genetic therapies to target cells. This non-enveloped virus has been trialed in many clinical-stage therapeutic strategies but important obstacle in ...
Wing Sum Chu, Joanne Ng
doaj +1 more source
A study of possibility of expression of an alternasucrase gene in sugar beet to produce alternan biopolymer [PDF]
مجله بیوتکنولوژی کشاورزی, 2020 Objective Lactic acid bacteria (LAB) synthesize valuable industrial and pharmaceutical important biopolymers, such as Alternan, by expressing glycosyltransferase enzymes by utilizing extracellular sucrose.
Farhad Nazarian-Firouzabadi +2 more
doaj +1 more source
Gene Therapy for Huntington’s Disease: The Final Strategy for a Cure? [PDF]
Journal of Movement Disorders, 2022 Huntington’s disease (HD) has become a target of the first clinical trials for gene therapy among movement disorders with a genetic origin. More than 100 clinical trials regarding HD have been tried, but all failed, although there were some improvements ...
Seulgi Byun, Mijung Lee, Manho Kim
doaj +1 more source
Frontiers in Immunology, 2020 Approximately 40% of preterm births are preceded by microbial invasion of the intrauterine space; ascent from the vagina being the most common pathway. Within the cervical canal, antimicrobial peptides and proteins (AMPs) are important components of the ...
Natalie Suff +16 more
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