Results 1 to 10 of about 1,625,963 (355)
Stable In-Planta Transformation System For Egyptian Sesame (Sesamum indicum L.) cv. Sohag 1
GM Crops & Food, 2023 Sesame (Sesamum indicum L.) is an important oil crop and one of the oldest-known oil crops to humankind. Sesame has excellent nutritional and therapeutic properties; it is rich in important fatty acids, protein, fiber, and vital minerals.
Esraa A. A. Sultan, Mohamed S. Tawfik
doaj +1 more source
Multiple pathways of plasmid DNA transfer in Helicobacter pylori [PDF]
, 2012 Many Helicobacter pylori (Hp) strains carry cryptic plasmids of different size and gene content, the function of which is not well understood. A subgroup of these plasmids (e.g.
Benghezal, Mohammed +5 more
core +7 more sources
Cells, 2023 Infantile parkinsonism-dystonia due to dopamine transporter deficiency syndrome (DTDS) is an ultrarare childhood movement disorder caused by biallelic loss-of-function mutations in the SLC6A3 gene.
Joanne Ng +3 more
doaj +1 more source
Immunomodulation in Administration of rAAV: Preclinical and Clinical Adjuvant Pharmacotherapies
Frontiers in Immunology, 2021 Recombinant adeno-associated virus (rAAV) has attracted a significant research focus for delivering genetic therapies to target cells. This non-enveloped virus has been trialed in many clinical-stage therapeutic strategies but important obstacle in ...
Wing Sum Chu, Joanne Ng
doaj +1 more source
Frontiers in Immunology, 2020 Approximately 40% of preterm births are preceded by microbial invasion of the intrauterine space; ascent from the vagina being the most common pathway. Within the cervical canal, antimicrobial peptides and proteins (AMPs) are important components of the ...
Natalie Suff +16 more
doaj +1 more source
Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders
EMBO Molecular Medicine, 2021 Gene therapy using recombinant adeno‐associated virus (rAAV) vectors to treat blinding retinal dystrophies has become clinical reality. Therapeutically impactful targeting of photoreceptors still relies on subretinal vector delivery, which detaches the ...
Marina Pavlou +16 more
doaj +1 more source
Gene transfer in the GI tract and oral cavity [PDF]
, 2000 Gene transfer is important in spreading antibiotic resistance and other traits such as virulence factors. In this review the molecular mechanisms of gene transfer are outlined and the biological consequences of bacterial gene transfer in the GI tract and
Mullany, P
core +1 more source
Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes
Journal of Hematology & Oncology, 2017 Background C5 blockade by eculizumab prevents complement-mediated intravascular hemolysis in paroxysmal nocturnal hemoglobinuria (PNH). However, C3-bound PNH red blood cells (RBCs), arising in almost all treated patients, may undergo extravascular ...
Michela Sica +5 more
doaj +1 more source
Genetic Diversity of Koala Retroviral Envelopes
Viruses, 2015 Genetic diversity, attributable to the low fidelity of reverse transcription, recombination and mutation, is an important feature of infectious retroviruses.
Wenqin Xu +4 more
doaj +1 more source
Perinatal Gene Transfer to the Liver [PDF]
, 2011 The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM +6 more
core +1 more source