Results 11 to 20 of about 5,395,678 (315)
xieyichun50/Horizontal-gene-transfer: Horizontal-gene-transfer-v1.0
Visualising horizontal gene transfer ...
Yichun
core +1 more source
A study of possibility of expression of an alternasucrase gene in sugar beet to produce alternan biopolymer [PDF]
Objective Lactic acid bacteria (LAB) synthesize valuable industrial and pharmaceutical important biopolymers, such as Alternan, by expressing glycosyltransferase enzymes by utilizing extracellular sucrose.
Farhad Nazarian-Firouzabadi +2 more
doaj +1 more source
Perinatal Gene Transfer to the Liver [PDF]
The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM +20 more
core +1 more source
Continual conscious bioluminescent imaging in freely moving somatotransgenic mice
Luciferase bioimaging in living animals is increasingly being applied in many fields of biomedical research. Rodent imaging usually involves anaesthetising the animal during data capture, however, the biological consequences of anaesthesia have been ...
Rajvinder Karda +11 more
doaj +1 more source
Direct in vivo gene transfer to the airway epithelium employing adenovirus-polylysine-DNA complexes [PDF]
Adenovirus-polylysine-DNA complexes were evaluated for their capacity to accomplish direct in vivo gene transfer to airway epithelium employing a rodent model.
Miller, L. +14 more
core +1 more source
Viral vectors are rapidly being developed for a range of applications in research and gene therapy. Prototype foamy virus (PFV) vectors have been described for gene therapy, although their use has mainly been restricted to ex vivo stem cell modification.
John R. Counsell +18 more
doaj +1 more source
DNA-based immunization induces a biased Th1 immune response, and offers a novel strategy for modulation of the Th2-associated response. Recent studies have provided evidence that antigen-induced allergic responses can be modulated in rodents immunized with plasmid DNAs encoding the sensitizing antigens. Further understanding of the regulatory mechanism
S K, Huang, K Y, Chua, K H, Hsieh
openaire +2 more sources
Integrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk [PDF]
We have previously shown that injury-induced neointima formation was rescued by adenoviral-Nogo-B gene delivery. Integrase-competent lentiviral vectors (ICLV) are efficient at gene delivery to vascular cells but present a risk of insertional mutagenesis.
Sessa, W.C. +10 more
core +1 more source
Carbohydrate receptor-mediated gene transfer to human T leukaemic cells [PDF]
The mucin-type carbohydrate Tn cryptantigen (GalNAcα1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins,
Berger, Eric G. +12 more
core +1 more source
Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway [PDF]
Gene-based therapies for a variety of inherited and acquired pulmonary diseases will require the development of vectors capable of safe and efficient transfer of DNA to the respiratory epithelium.
Boucher, R. C. +14 more
core +1 more source

