Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang +13 more
wiley +1 more source
Eight Women With Autologous Fat Transfer and Deep Inferior Epigastric Perforator Flap Breast Reconstruction: Which Do They Prefer, and Why? [PDF]
van der Venne WBW +5 more
europepmc +1 more source
The collagen nanofiber (CNF) gel supports cancer cell culture, exhibiting cell morphology and cancer‐related protein expression similar to Matrigel. It offers a higher collagen concentration than commercial gels. Additionally, the CNF gel allows replication of the high elasticity of in vivo cancer tissue by controlling collagen fiber sizes, ranging ...
Naoko Sasaki +4 more
wiley +1 more source
Boron-doped diamond solution-gate field-effect transistor (BDD-SGFET) biosensor for gene mutation detection. [PDF]
Lin Z, Zheng Y, Chen Y, Wang C, Yuan Z.
europepmc +1 more source
A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn +7 more
wiley +1 more source
Progress in (Photo)electrochemical Biosensors for the Detection of Amyloid-Beta Oligomer. [PDF]
Huang Y, Wang N, Yi X, Xia N.
europepmc +1 more source
A 3D Human Neuron‐on‐Chip Platform to Monitor Neuronal Injury Responses
This study presents a novel 3D Neuron‐on‐Chip model that can maintain human PSC‐derived excitatory prefrontal cortex neurons in 3D hydrogels and can be used to monitor neuronal injury responses over time. Results show injury‐induced acute neuronal excitotoxicity, declining neuronal connectivity, and the activation of a neurodegenerative, SASP‐like ...
Ruiping Tang +16 more
wiley +1 more source
DestinyNet: A deep-learning framework for cell-fate analysis from lineage-tracing single-cell RNA sequencing data. [PDF]
Liu Z +13 more
europepmc +1 more source
Decoding Treatment Response in Hepatocellular Carcinoma: The Era of Radiomics and Radiogenomics. [PDF]
Wang Z, Gan W, Gong J, Li X.
europepmc +1 more source
Extracellular Vesicle-Mediated Communication in Sellar Tumors: A Conceptual and Translational Framework. [PDF]
Veiceschi P +5 more
europepmc +1 more source

