Results 91 to 100 of about 77,183 (300)

Modulatory mechanism of the paraventricular thalamus (PVT) under general anesthesia

Frontiers in Pharmacology
The paraventricular thalamus (PVT) is a critical brain region involved in controlling sleep-wakefulness. Many neural nuclei and circuits regulate consciousness under both sleep-wakefulness and general anesthesia, suggesting that a common neural mechanism
Jia Li, Yiyong Wei, Donghang Zhang
doaj   +1 more source

Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients

Arthritis Care &Research, EarlyView.
Objective Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla, Timothy G. Brandon, Dmitry Khrichenko, Rui Xiao, Nancy A. Chauvin, Asef Khwaja, Pamela F. Weiss   +6 more
wiley   +1 more source

Using the adjuvants during infusion of local anaestetics into caudal-epidural space in newborns

Patologìâ, 2012
Markers of stress and central haemodynamics were investigated in 45 newborns. General anesthesia and caudal infusion of local anesthetics were combined in 15 newborns. Promedol and clonidine were added to local anesthetics in 15 newborns.
M. Yu. Kurochkin
doaj   +1 more source

Perioperative Neurocognitive Disorder: State of the Preclinical Science. [PDF]

, 2020
The purpose of this article is to provide a succinct summary of the different experimental approaches that have been used in preclinical postoperative cognitive dysfunction research, and an overview of the knowledge that has accrued. This is not intended
Culley, Deborah J, Eckenhoff, Maryellen F, Eckenhoff, Roderic G, Goodlin, Sarah J, Maze, Mervyn, Orser, Beverley A, Terrando, Niccolò, Wei, Huafeng, Whittington, Robert A, Xie, Zhongcong, Zuo, Zhiyi   +10 more
core  

Accuracy of Diagnostic Codes and Algorithms Used to Identify Rheumatoid Arthritis and Juvenile Idiopathic Arthritis in Administrative Claims and Electronic Health Records: Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in electronic health records. Methods We searched Medline, Embase, and Cochrane Central Register for Controlled Trials databases and included studies that validated case definitions against a ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Involvement of the parabrachial nucleus in emergence from general anesthesia

Frontiers in Neuroscience
The parabrachial nucleus (PBN), located in the dorsolateral pons, is involved in many important biological functions, such as sensory signaling, feeding, defensive behaviors, fear, anxiety, and sleep–wake cycles.
Jia Li, Qiuyu Zhu, Jiaxin Xiang, Yiyong Wei, Donghang Zhang   +4 more
doaj   +1 more source

Financial Distress and Its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

Dual effects of GABAAR agonist anesthetics in neurodevelopment and vulnerable brains: From neurotoxic to therapeutic effects

Neural Regeneration Research
Debates regarding the specific effects of general anesthesia on developing brains have persisted for over 30 years. A consensus has been reached that prolonged, repeated, high-dose exposure to anesthetics is associated with a higher incidence of deficits
Dihan Lu, Wen Zhang, Keyu Chen, Xia Feng
doaj   +1 more source

Testing a Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

Arthritis Care &Research, EarlyView.
Objective We aimed to test the efficacy of personalized treatment of older veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABCs) as compared with usual care (UC). Methods Two hundred ninety‐nine veterans aged 65 to 89 with CLBP from three Veterans Affairs (VA) medical centers underwent baseline testing, randomization to ABC ...
Debra K. Weiner, Angela Gentili, Meika A. Fang, Edward Garay, Laura Lawson, Lenore Joseph, Cathy C. Lee, Michelle I. Rossi, Beverly Thorn, Subashan Perera   +9 more
wiley   +1 more source

Environmental enrichment enhances anesthetic actions in rat amygdala hippocampal circuits in vitro

Frontiers in Pharmacology
IntroductionEnvironmental enrichment enhances hippocampal synaptic plasticity, yet its influence on anesthetic action remains poorly understood. This study tested the hypothesis that enriched environment (EE) rearing modifies the inhibitory effects of ...
Kenta Onishi, Rika Sasaki, Koki Hirota, Tomonori Takazawa   +3 more
doaj   +1 more source