Results 91 to 100 of about 932,090 (364)

Parosmia and dysgeusia after intravenous propofol-based general anesthesia: A case report

Annals of Cardiac Anaesthesia, 2022
Various drugs, including anesthetic agents, can cause parosmia in the perioperative period. There are reported cases of patients with alterations of smell and taste due to local anesthetics, nerve damage, or as a side effect of general anesthesia.
Nayab Farzana, Prabhat Tewari, Sanjoy Sureka, Aanchal Dixit   +3 more
doaj   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

Intravenous anesthetics have differential effects on human potassium channels

Acta Biochimica et Biophysica Sinica
General anesthetics are widely used in the clinic and greatly promote the development of surgery. However, the incidence of cardiovascular and respiratory complications caused by general anesthetics is still high, and the underlying mechanisms remain ...
Tao Ying, Yao Kejie, Wu Jing, Xu Tian, Lin Junhui, Qin Yi, Su Diansan, Cai Shiqing, Yu Weifeng, Chen Xuemei   +9 more
doaj   +1 more source

Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels

Cell Reports, 2018
Summary: Ion channel modulation by general anesthetics is a vital pharmacological process with implications for receptor biophysics and drug development. Functional studies have implicated conserved sites of both potentiation and inhibition in pentameric
Zaineb Fourati, Rebecca J. Howard, Stephanie A. Heusser, Haidai Hu, Reinis R. Ruza, Ludovic Sauguet, Erik Lindahl, Marc Delarue   +7 more
doaj  

Involvement of the parabrachial nucleus in emergence from general anesthesia

Frontiers in Neuroscience
The parabrachial nucleus (PBN), located in the dorsolateral pons, is involved in many important biological functions, such as sensory signaling, feeding, defensive behaviors, fear, anxiety, and sleep–wake cycles.
Jia Li, Qiuyu Zhu, Jiaxin Xiang, Yiyong Wei, Donghang Zhang   +4 more
doaj   +1 more source

Combined Systemic Immunotherapy and Intrathecal Dexamethasone in Febrile Infection Related Epilepsy Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Febrile infection related epilepsy syndrome (FIRES) is a rare presentation of refractory status epilepticus with immune dysregulation as a potential pathologic mechanism. Despite promising results from second‐line immunomodulators, approximately 30% remain refractory to treatment.
Kristen S. Fisher, Alexander Ankar, Jon Cokley, Eyal Muscal, James J. Riviello, Yi‐Chen Lai   +5 more
wiley   +1 more source

Dual effects of GABAAR agonist anesthetics in neurodevelopment and vulnerable brains: From neurotoxic to therapeutic effects

Neural Regeneration Research
Debates regarding the specific effects of general anesthesia on developing brains have persisted for over 30 years. A consensus has been reached that prolonged, repeated, high-dose exposure to anesthetics is associated with a higher incidence of deficits
Dihan Lu, Wen Zhang, Keyu Chen, Xia Feng
doaj   +1 more source

General anesthetics inhibit LPS-induced IL-1β expression in glial cells. [PDF]

PLoS ONE, 2013
BACKGROUND: Glial cells, including microglia and astrocytes, are considered the primary source of proinflammatory cytokines in the brain. Immune insults stimulate glial cells to secrete proinflammatory cytokines that modulate the acute systemic response,
Tomoharu Tanaka, Shinichi Kai, Tomonori Matsuyama, Takehiko Adachi, Kazuhiko Fukuda, Kiichi Hirota   +5 more
doaj   +1 more source

Chloride of Ethyl as a General Anesthetic [PDF]

The Boston Medical and Surgical Journal, 1903
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openaire   +3 more sources

Are General anesthetics neurotoxic?

International Archives of Medicine, 2015
Introduction: General anaesthesia has been used worldwide since its first public demonstration with ether in 1846. Until a little more than a decade ago, it was believed that the anaesthetic state was limited to the period of exposure. Studies in rats, pigs, and rhesus monkeys have shown that almost all general anaesthetics accelerate the apoptotic ...
Breno Souza Benevides, Luiz Carlos de Abreu, Leonardo Araújo Sampaio, Naidhia Alves Soares Ferreira, Gylmara Bezerra de Menezes Silveira, Italla Maria Pinheiro Bezerra, Márcio Fernando Gonçalves Araújo, Vitor Engrácia Valenti, Hermes Melo Teixeira Batista, Maria Manuela Martins Rolim   +9 more
openaire   +2 more sources