Results 81 to 90 of about 11,135,694 (289)
Apical Function in Neocortical Pyramidal Cells: A Common Pathway by Which General Anesthetics Can Affect Mental State [PDF]
, 2018 It has been argued that general anesthetics suppress the level of consciousness, or the contents of consciousness, or both. The distinction between level and content is important because, in addition to clarifying the mechanisms of anesthesia, it may ...
Storm, Johan Frederik +6 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source
Environmental enrichment enhances anesthetic actions in rat amygdala hippocampal circuits in vitro
Frontiers in PharmacologyIntroductionEnvironmental enrichment enhances hippocampal synaptic plasticity, yet its influence on anesthetic action remains poorly understood. This study tested the hypothesis that enriched environment (EE) rearing modifies the inhibitory effects of ...
Kenta Onishi +3 more
doaj +1 more source
ETHYL CHLORID AS A GENERAL ANESTHETIC. [PDF]
JAMA: The Journal of the American Medical Association, 1906 I have lately noticed inThe Journalvarious articles on the use of ethyl chlorid as a short general anesthetic, and some specially constructed masks. To my mind the latter are too expensive for the general practitioner, and I desire to present a method that I use in the receiving ward of the Cincinnati Hospital.
openaire +1 more source
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Arthritis Care &Research, EarlyView.Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
How do General Anesthetics Work?
, 2019 General anesthesia is one of the most important advances in medical history allowing the execution of medical procedures that would be too painful to tolerate for conscious patients. Despite over 170 years of general clinical practice in Western medicine,
Türkyılmaz, Serhan
core +1 more source
General anesthetics inhibit cytochrome P450 monooxygenases and arachidonic acid metabolism
, 1993 Identification of a specific biomolecular target appropriately sensitive to a wide array of anesthetics has been elusive. At concentrations close to their respective ED50's for anesthesia in man or other species, 18 compounds, differing in potencies up ...
Gary Queen, Frank S. LaBella
core +1 more source
PATIENT DRUG GUIDE SERIES: ANESTHETICS
, 2020 This Honors Thesis is comprised of an original body of work in the form of a series of patient drug guides. Specifically, this collection consists of pamphlets describing commonly used anesthetics for surgical use written at an 8th-grade reading level ...
Louis, Emma
core +2 more sources
Drug Challenge Tests With General Anesthetics: Predictive Value of Skin Tests
, 2019 Background: The study of perioperative drug reactions remains a major challenge for both diagnosis and therapy. The lack of a standard assessment of allergy to general anesthetics and of data establishing the true value of skin tests for most drugs used ...
Tornero Molina, P. +6 more
core +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Arthritis Care &Research, EarlyView.Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source