Results 61 to 70 of about 45,779 (252)

Evaluation of a Novel Electric Health Record Sidecar Application to Display Rheumatoid Arthritis Clinical Outcomes During Clinic Visits: Results of a Stepped‐Wedge Cluster Randomized Pragmatic Trial

open access: yesArthritis Care &Research, EarlyView.
Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk   +16 more
wiley   +1 more source

Environmental enrichment enhances anesthetic actions in rat amygdala hippocampal circuits in vitro

open access: yesFrontiers in Pharmacology
IntroductionEnvironmental enrichment enhances hippocampal synaptic plasticity, yet its influence on anesthetic action remains poorly understood. This study tested the hypothesis that enriched environment (EE) rearing modifies the inhibitory effects of ...
Kenta Onishi   +3 more
doaj   +1 more source

Effects of general anesthetics on visceral pain transmission in the spinal cord

open access: yesMolecular Pain, 2008
Current evidence suggests an analgesic role for the spinal cord action of general anesthetics; however, the cellular population and intracellular mechanisms underlying anti-visceral pain by general anesthetics still remain unclear.
Yue Yun   +5 more
doaj   +1 more source

ETHYL CHLORID AS A GENERAL ANESTHETIC. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1906
I have lately noticed inThe Journalvarious articles on the use of ethyl chlorid as a short general anesthetic, and some specially constructed masks. To my mind the latter are too expensive for the general practitioner, and I desire to present a method that I use in the receiving ward of the Cincinnati Hospital.
openaire   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

open access: yesArthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King   +10 more
wiley   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

open access: yesArthritis Care &Research, EarlyView.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández   +10 more
wiley   +1 more source

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

open access: yesArthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

Using the adjuvants during infusion of local anaestetics into caudal-epidural space in newborns

open access: yesPatologìâ, 2012
Markers of stress and central haemodynamics were investigated in 45 newborns. General anesthesia and caudal infusion of local anesthetics were combined in 15 newborns. Promedol and clonidine were added to local anesthetics in 15 newborns.
M. Yu. Kurochkin
doaj   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

open access: yesArthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik   +5 more
wiley   +1 more source

Modulatory mechanism of the paraventricular thalamus (PVT) under general anesthesia

open access: yesFrontiers in Pharmacology
The paraventricular thalamus (PVT) is a critical brain region involved in controlling sleep-wakefulness. Many neural nuclei and circuits regulate consciousness under both sleep-wakefulness and general anesthesia, suggesting that a common neural mechanism
Jia Li, Yiyong Wei, Donghang Zhang
doaj   +1 more source

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